Source: CURATED

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 9378
Gene Symbol: NRXN1
NRXN1
neurexin 1 0.581 0.692 1.00
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
disease 0.700 None 0.962 4 0 2007 2019
Entrez Id: 57680
Gene Symbol: CHD8
CHD8
chromodomain helicase DNA binding protein 8 0.656 0.577 1.00
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
disease 0.700 moderate 1.000 2 1 2012 2019
Entrez Id: 10716
Gene Symbol: TBR1
TBR1
T-box brain transcription factor 1 0.666 0.385 1.00
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
disease 0.650 None 1.000 1 0 2012 2017
Entrez Id: 5080
Gene Symbol: PAX6
PAX6
paired box 6 0.450 0.769 1.00
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
disease 0.530 None 1.000 1 0 2008 2014
Entrez Id: 50944
Gene Symbol: SHANK1
SHANK1
SH3 and multiple ankyrin repeat domains 1 0.678 0.385 1.00
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
disease 0.530 None 1.000 1 0 2008 2018
Entrez Id: 2332
Gene Symbol: FMR1
FMR1
FMRP translational regulator 1 0.473 0.769 0.65
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
disease 0.500 None 0.965 5 0 1992 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.305 0.923 0.26
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
disease 0.500 None 1.000 4 2 2001 2020
Entrez Id: 26047
Gene Symbol: CNTNAP2
CNTNAP2
contactin associated protein 2 0.530 0.846 2.9E-09
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
disease 0.500 None 0.975 4 1 2008 2019
Entrez Id: 4128
Gene Symbol: MAOA
MAOA
monoamine oxidase A 0.465 0.769 1.00
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
disease 0.500 None 1.000 3 0 1999 2020
Entrez Id: 7337
Gene Symbol: UBE3A
UBE3A
ubiquitin protein ligase E3A 0.561 0.692 1.00
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
disease 0.500 None 1.000 3 0 1999 2019
Entrez Id: 4204
Gene Symbol: MECP2
MECP2
methyl-CpG binding protein 2 0.414 0.846 0.89
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
disease 0.500 None 0.919 3 3 2000 2019
Entrez Id: 85358
Gene Symbol: SHANK3
SHANK3
SH3 and multiple ankyrin repeat domains 3 0.550 0.731 1.00
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
disease 0.500 None 1.000 2 0 2005 2019
Entrez Id: 54413
Gene Symbol: NLGN3
NLGN3
neuroligin 3 0.653 0.462 0.98
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
disease 0.500 None 1.000 2 0 2003 2019
Entrez Id: 57502
Gene Symbol: NLGN4X
NLGN4X
neuroligin 4 X-linked 0.686 0.423 0.99
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
disease 0.500 None 0.926 1 0 2003 2019
Entrez Id: 23394
Gene Symbol: ADNP
ADNP
activity dependent neuroprotector homeobox 0.561 0.808 1.00
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
disease 0.500 None 1.000 1 1 2014 2019
Entrez Id: 11141
Gene Symbol: IL1RAPL1
IL1RAPL1
interleukin 1 receptor accessory protein like 1 0.617 0.692 1.00
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
disease 0.460 None 1.000 2 0 2008 2013
Entrez Id: 55217
Gene Symbol: TMLHE
TMLHE
trimethyllysine hydroxylase, epsilon 0.821 0.231 8.0E-05
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
disease 0.460 None 1.000 0 0 2011 2017
Entrez Id: 7249
Gene Symbol: TSC2
TSC2
TSC complex subunit 2 0.439 0.808 1.00
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
disease 0.450 None 1.000 1 0 2003 2017
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C
calcium voltage-gated channel subunit alpha1 C 0.510 0.846 1.00
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
disease 0.450 None 1.000 1 0 2004 2019
Entrez Id: 8242
Gene Symbol: KDM5C
KDM5C
lysine demethylase 5C 0.581 0.538 1.00
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
disease 0.440 None 1.000 1 0 2008 2019
Entrez Id: 158
Gene Symbol: ADSL
ADSL
adenylosuccinate lyase 0.631 0.654 8.9E-12
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
disease 0.430 None 1.000 1 0 1989 2004
Entrez Id: 8831
Gene Symbol: SYNGAP1
SYNGAP1
synaptic Ras GTPase activating protein 1 0.584 0.577 1.00
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
disease 0.430 None 1.000 1 0 2010 2019
Entrez Id: 140733
Gene Symbol: MACROD2
MACROD2
mono-ADP ribosylhydrolase 2 0.686 0.423 0.43
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
disease 0.430 None 1.000 1 4 2010 2019
Entrez Id: 139411
Gene Symbol: PTCHD1
PTCHD1
patched domain containing 1 0.678 0.385 0.98
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
disease 0.430 None 1.000 1 0 2011 2017
Entrez Id: 2904
Gene Symbol: GRIN2B
GRIN2B
glutamate ionotropic receptor NMDA type subunit 2B 0.510 0.692 1.00
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
disease 0.430 strong 1.000 1 2 2013 2018