| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
APC, WNT signaling pathway regulator | 0.397 | 0.828 | 1.00 |
|
disease | 0.600 | 0.937 | 243 | 7 | 1990 | 2018 | |||||||||
|
DCC netrin 1 receptor | 0.504 | 0.655 | 0.99 |
|
disease | 0.600 | 0.906 | 34 | 2 | 1990 | 2015 | |||||||||
|
KRAS proto-oncogene, GTPase | 0.350 | 0.724 | 9.0E-04 |
|
disease | 0.400 | 0.963 | 494 | 7 | 1992 | 2018 | |||||||||
|
tumor protein p53 | 0.251 | 0.897 | 0.17 |
|
disease | 0.400 | 0.946 | 411 | 9 | 1989 | 2018 | |||||||||
|
epidermal growth factor receptor | 0.325 | 0.862 | 0.50 |
|
disease | 0.400 | 0.956 | 318 | 4 | 1992 | 2018 | |||||||||
|
B-Raf proto-oncogene, serine/threonine kinase | 0.352 | 0.793 | 1.00 |
|
disease | 0.400 | 0.970 | 304 | 2 | 2002 | 2018 | |||||||||
|
mutL homolog 1 | 0.424 | 0.759 | 5.1E-05 |
|
disease | 0.400 | 0.967 | 276 | 11 | 1993 | 2018 | |||||||||
|
mutS homolog 2 | 0.437 | 0.690 | 0.91 |
|
disease | 0.400 | 0.953 | 171 | 5 | 1993 | 2017 | |||||||||
|
prostaglandin-endoperoxide synthase 2 | 0.338 | 0.897 | 1.00 |
|
disease | 0.400 | 0.971 | 146 | 7 | 1998 | 2018 | |||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.341 | 0.897 | 1.00 |
|
disease | 0.400 | 1.000 | 120 | 1 | 2004 | 2018 | |||||||||
|
thymidylate synthetase | 0.457 | 0.759 | 0.76 |
|
disease | 0.400 | 0.919 | 92 | 2 | 1997 | 2018 | |||||||||
|
methylenetetrahydrofolate reductase | 0.354 | 0.828 | 1.2E-09 |
|
disease | 0.400 | 0.914 | 76 | 7 | 1997 | 2018 | |||||||||
|
SMAD family member 4 | 0.430 | 0.759 | 1.00 |
|
disease | 0.400 | 0.981 | 54 | 0 | 1996 | 2018 | |||||||||
|
BCL2, apoptosis regulator | 0.312 | 0.862 | 0.57 |
|
disease | 0.400 | 1.000 | 49 | 0 | 1997 | 2018 | |||||||||
|
AKT serine/threonine kinase 1 | 0.355 | 0.862 | 0.98 |
|
disease | 0.400 | 0.894 | 47 | 1 | 2002 | 2018 | |||||||||
|
catenin beta 1 | 0.417 | 0.759 | 1.00 |
|
disease | 0.400 | 1.000 | 46 | 0 | 1998 | 2017 | |||||||||
|
ATP binding cassette subfamily B member 1 | 0.371 | 0.828 | 1.3E-05 |
|
disease | 0.400 | 0.923 | 40 | 5 | 1990 | 2018 | |||||||||
|
glutathione S-transferase mu 1 | 0.403 | 0.828 | 2.0E-03 |
|
disease | 0.400 | 0.895 | 39 | 2 | 1995 | 2017 | |||||||||
|
tumor necrosis factor | 0.263 | 0.966 | 0.80 |
|
disease | 0.400 | 1.000 | 38 | 1 | 1989 | 2017 | |||||||||
|
dihydropyrimidine dehydrogenase | 0.520 | 0.690 | 5.7E-22 |
|
disease | 0.400 | 0.967 | 34 | 1 | 1998 | 2018 | |||||||||
|
peroxisome proliferator activated receptor gamma | 0.388 | 0.828 | 0.14 |
|
disease | 0.400 | 0.882 | 34 | 4 | 2000 | 2015 | |||||||||
|
SMAD family member 7 | 0.520 | 0.621 | 0.56 |
|
disease | 0.400 | 1.000 | 33 | 7 | 2001 | 2018 | |||||||||
|
prominin 1 | 0.450 | 0.793 | 2.4E-18 |
|
disease | 0.400 | 0.906 | 33 | 0 | 2008 | 2017 | |||||||||
|
insulin like growth factor 2 | 0.399 | 0.828 | 4.7E-02 |
|
disease | 0.400 | 1.000 | 31 | 0 | 1996 | 2017 | |||||||||
|
transforming growth factor beta 1 | 0.336 | 0.931 | 0.17 |
|
disease | 0.400 | 0.964 | 29 | 0 | 1994 | 2018 |