| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
mutL homolog 1 | 0.399 | 0.808 | 3.4E-05 |
|
disease | 0.800 | strong | 0.973 | 485 | 32 | 1993 | 2020 | ||||||||
|
APC regulator of WNT signaling pathway | 0.373 | 0.962 | 1.00 |
|
disease | 0.800 | strong | 0.972 | 359 | 34 | 1990 | 2020 | ||||||||
|
mutS homolog 2 | 0.406 | 0.808 | 0.90 |
|
disease | 0.800 | strong | 0.971 | 277 | 18 | 1993 | 2020 | ||||||||
|
NRAS proto-oncogene, GTPase | 0.390 | 0.808 | 0.49 |
|
disease | 0.800 | strong | 0.966 | 59 | 6 | 1993 | 2020 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.700 | None | 0.947 | 665 | 19 | 1989 | 2020 | ||||||||
|
B-Raf proto-oncogene, serine/threonine kinase | 0.319 | 0.846 | 1.00 |
|
disease | 0.700 | None | 0.976 | 622 | 10 | 2002 | 2020 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
disease | 0.700 | None | 0.983 | 469 | 8 | 1997 | 2020 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.700 | None | 0.985 | 266 | 13 | 2002 | 2020 | ||||||||
|
SMAD family member 4 | 0.401 | 0.808 | 1.00 |
|
disease | 0.700 | strong | 0.981 | 103 | 3 | 1996 | 2020 | ||||||||
|
DCC netrin 1 receptor | 0.471 | 0.808 | 0.99 |
|
disease | 0.700 | None | 0.946 | 56 | 3 | 1990 | 2019 | ||||||||
|
matrix metallopeptidase 2 | 0.333 | 0.923 | 0.84 |
|
disease | 0.700 | None | 1.000 | 46 | 4 | 1992 | 2019 | ||||||||
|
transcription factor 7 like 2 | 0.485 | 0.846 | 1.00 |
|
disease | 0.700 | None | 0.925 | 40 | 5 | 1999 | 2019 | ||||||||
|
checkpoint kinase 2 | 0.460 | 0.808 | 1.2E-24 |
|
disease | 0.700 | limited | 0.885 | 26 | 5 | 2003 | 2019 | ||||||||
|
SMAD family member 3 | 0.415 | 0.923 | 0.80 |
|
disease | 0.700 | None | 0.941 | 17 | 1 | 1998 | 2019 | ||||||||
|
BUB1 mitotic checkpoint serine/threonine kinase | 0.528 | 0.731 | 4.9E-09 |
|
disease | 0.700 | None | 1.000 | 10 | 4 | 2000 | 2018 | ||||||||
|
fibroblast growth factor receptor 3 | 0.391 | 0.846 | 1.6E-05 |
|
disease | 0.660 | None | 1.000 | 6 | 8 | 2000 | 2018 | ||||||||
|
Kruppel like factor 5 | 0.534 | 0.769 | 0.82 |
|
disease | 0.640 | None | 1.000 | 6 | 2 | 2011 | 2019 | ||||||||
|
E1A binding protein p300 | 0.459 | 0.846 | 1.00 |
|
disease | 0.640 | None | 1.000 | 5 | 4 | 1996 | 2017 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
disease | 0.600 | None | 0.963 | 1007 | 13 | 1990 | 2020 | ||||||||
|
AKT serine/threonine kinase 1 | 0.311 | 0.962 | 0.98 |
|
disease | 0.600 | limited | 0.984 | 123 | 1 | 2002 | 2020 | ||||||||
|
mutS homolog 6 | 0.462 | 0.731 | 3.7E-05 |
|
disease | 0.600 | strong | 0.974 | 114 | 36 | 1988 | 2020 | ||||||||
|
ATP binding cassette subfamily B member 1 | 0.344 | 0.885 | 1.3E-05 |
|
disease | 0.600 | None | 0.960 | 75 | 7 | 1990 | 2020 | ||||||||
|
kinase insert domain receptor | 0.378 | 0.885 | 1.00 |
|
disease | 0.600 | None | 0.964 | 28 | 0 | 2002 | 2019 | ||||||||
|
DNA polymerase epsilon, catalytic subunit | 0.526 | 0.731 | 8.0E-27 |
|
disease | 0.600 | strong | 1.000 | 28 | 5 | 2013 | 2020 | ||||||||
|
insulin like growth factor binding protein 3 | 0.439 | 0.808 | 0.91 |
|
disease | 0.600 | None | 0.815 | 27 | 4 | 2004 | 2019 |