×
Entrez Id:
3630
Gene Symbol:
INS
INS
Diabetes Mellitus, Insulin-Dependent
0.700
Biomarker
MGD
Integrin α1/Akita double-knockout mice on a Balb/c background develop advanced features of human diabetic nephropathy.
22297672
2012
×
Entrez Id:
3630
Gene Symbol:
INS
INS
Diabetes Mellitus, Insulin-Dependent
0.700
Biomarker
MGD
Evidence for a primary islet autoantigen (preproinsulin 1) for insulitis and diabetes in the nonobese diabetic mouse.
12925730
2003
×
Entrez Id:
3458
Gene Symbol:
IFNG
IFNG
Diabetes Mellitus, Insulin-Dependent
0.600
Biomarker
MGD
IFN-gamma affects homing of diabetogenic T cells.
11714835
2001
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Diabetes Mellitus, Insulin-Dependent
0.300
Biomarker
MGD
Late developmental plasticity in the T helper 17 lineage.
19119024
2009
×
Entrez Id:
2572
Gene Symbol:
GAD2
GAD2
Diabetes Mellitus, Insulin-Dependent
0.300
Biomarker
MGD
To investigate the role of glutamic acid decarboxylase 65 (GAD65 ) in the development of the Type 1 diabetes of non-obese diabetic (NOD) mice, we analysed and characterised NOD mice with targeted disruption of the GAD65 gene.
14676944
2004
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Diabetes Mellitus, Insulin-Dependent
0.300
Biomarker
MGD
Autoimmune diabetes is blocked in Stat4-deficient mice.
15041039
2004
×
Entrez Id:
6775
Gene Symbol:
STAT4
STAT4
Diabetes Mellitus, Insulin-Dependent
0.300
Biomarker
MGD
Contrasting roles for STAT4 and STAT6 signal transduction pathways in murine renal ischemia-reperfusion injury.
12709397
2003
×
Entrez Id:
3565
Gene Symbol:
IL4
IL4
Diabetes Mellitus, Insulin-Dependent
0.300
Biomarker
MGD
Interleukin-4 deficiency does not exacerbate disease in NOD mice.
9703318
1998
×
Entrez Id:
4760
Gene Symbol:
NEUROD1
NEUROD1
Diabetes Mellitus, Insulin-Dependent
0.300
Biomarker
MGD
Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice.
9308961
1997
×
Entrez Id:
3481
Gene Symbol:
IGF2
IGF2
Diabetes Mellitus, Insulin-Dependent
0.300
Biomarker
MGD
×
Entrez Id:
57818
Gene Symbol:
G6PC2
G6PC2
Diabetes Mellitus, Insulin-Dependent
0.300
Biomarker
MGD
×
Entrez Id:
5799
Gene Symbol:
PTPRN2
PTPRN2
Diabetes Mellitus, Insulin-Dependent
0.300
Biomarker
MGD
×
Entrez Id:
3651
Gene Symbol:
PDX1
PDX1
Diabetes Mellitus, Insulin-Dependent
0.260
Biomarker
MGD
×
Entrez Id:
4843
Gene Symbol:
NOS2
NOS2
Diabetes Mellitus, Insulin-Dependent
0.250
Biomarker
MGD
×
Entrez Id:
3554
Gene Symbol:
IL1R1
IL1R1
Diabetes Mellitus, Insulin-Dependent
0.240
Biomarker
MGD
IL-1 receptor deficiency slows progression to diabetes in the NOD mouse.
14693705
2004
×
Entrez Id:
952
Gene Symbol:
CD38
CD38
Diabetes Mellitus, Insulin-Dependent
0.220
Biomarker
MGD
Targeted disruption of CD38 accelerates autoimmune diabetes in NOD/Lt mice by enhancing autoimmunity in an ADP-ribosyltransferase 2-dependent fashion.
16585549
2006
×
Entrez Id:
6402
Gene Symbol:
SELL
SELL
Diabetes Mellitus, Insulin-Dependent
0.220
Biomarker
MGD
Changes in the expression of many Ets family transcription factors and of potential target genes in normal mammary tissue and tumors.
14662758
2004
×
Entrez Id:
1019
Gene Symbol:
CDK4
CDK4
Diabetes Mellitus, Insulin-Dependent
0.220
Biomarker
MGD
Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia.
10319860
1999
×
Entrez Id:
356
Gene Symbol:
FASLG
FASLG
Diabetes Mellitus, Insulin-Dependent
0.220
Biomarker
MGD
×
Entrez Id:
7292
Gene Symbol:
TNFSF4
TNFSF4
Diabetes Mellitus, Insulin-Dependent
0.210
Biomarker
MGD
Paradoxical dampening of anti-islet self-reactivity but promotion of diabetes by OX40 ligand.
14662903
2003
×
Entrez Id:
5551
Gene Symbol:
PRF1
PRF1
Diabetes Mellitus, Insulin-Dependent
0.210
Biomarker
MGD
Islet-specific expression of IL-10 promotes diabetes in nonobese diabetic mice independent of Fas, perforin, TNF receptor-1, and TNF receptor-2 molecules.
10946317
2000
×
Entrez Id:
11213
Gene Symbol:
IRAK3
IRAK3
Diabetes Mellitus, Insulin-Dependent
0.200
Biomarker
MGD
IRAK-M deficiency promotes the development of type 1 diabetes in NOD mice.
24696448
2014
×
Entrez Id:
1869
Gene Symbol:
E2F1
E2F1
Diabetes Mellitus, Insulin-Dependent
0.200
Biomarker
MGD
Consistent with these observations, E2f1 homozygous mutant NOD mice were highly predisposed to the development of IDDM and SS.
15470032
2004
×
Entrez Id:
3460
Gene Symbol:
IFNGR2
IFNGR2
Diabetes Mellitus, Insulin-Dependent
0.200
Biomarker
MGD
IFN-gamma affects homing of diabetogenic T cells.
11714835
2001
×
Entrez Id:
3460
Gene Symbol:
IFNGR2
IFNGR2
Diabetes Mellitus, Insulin-Dependent
0.200
Biomarker
MGD
Interferon-gamma receptor signaling is dispensable in the development of autoimmune type 1 diabetes in NOD mice.
11118001
2000