| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
insulin | 0.445 | 0.923 | 0.30 |
|
disease | 0.700 | None | 1.000 | 27 | 2 | 1994 | 2019 | ||||||||
|
protein kinase C beta | 0.453 | 0.885 | 1.00 |
|
disease | 0.540 | None | 1.000 | 6 | 0 | 1999 | 2019 | ||||||||
|
glucokinase | 0.523 | 0.808 | 0.63 |
|
disease | 0.500 | None | 1.000 | 127 | 23 | 1992 | 2020 | ||||||||
|
insulin receptor | 0.432 | 0.846 | 3.6E-05 |
|
disease | 0.500 | None | 0.966 | 29 | 0 | 1984 | 2019 | ||||||||
|
HNF1 homeobox A | 0.478 | 0.846 | 0.96 |
|
disease | 0.500 | None | 0.964 | 28 | 5 | 1996 | 2020 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.500 | None | 1.000 | 23 | 1 | 2005 | 2020 | ||||||||
|
glucagon | 0.431 | 0.885 | 3.5E-02 |
|
disease | 0.400 | None | 0.966 | 116 | 0 | 1975 | 2020 | ||||||||
|
leptin | 0.349 | 0.846 | 0.46 |
|
disease | 0.400 | None | 1.000 | 25 | 0 | 2009 | 2019 | ||||||||
|
nuclear factor, erythroid 2 like 2 | 0.357 | 0.885 | 3.6E-03 |
|
disease | 0.400 | None | 1.000 | 23 | 0 | 2008 | 2020 | ||||||||
|
adiponectin, C1Q and collagen domain containing | 0.376 | 0.885 | 4.6E-09 |
|
disease | 0.400 | None | 1.000 | 18 | 1 | 2004 | 2019 | ||||||||
|
advanced glycosylation end-product specific receptor | 0.420 | 0.885 | 6.4E-16 |
|
disease | 0.400 | None | 1.000 | 14 | 0 | 2009 | 2019 | ||||||||
|
pancreatic and duodenal homeobox 1 | 0.530 | 0.654 | 1.8E-02 |
|
disease | 0.400 | None | 1.000 | 14 | 0 | 1999 | 2018 | ||||||||
|
nitric oxide synthase 3 | 0.378 | 0.885 | 6.7E-07 |
|
disease | 0.400 | None | 1.000 | 13 | 1 | 2001 | 2020 | ||||||||
|
C-C motif chemokine ligand 2 | 0.321 | 0.962 | 0.61 |
|
disease | 0.400 | None | 1.000 | 13 | 0 | 2010 | 2019 | ||||||||
|
prostaglandin-endoperoxide synthase 2 | 0.314 | 0.962 | 1.00 |
|
disease | 0.350 | None | 1.000 | 5 | 0 | 2003 | 2017 | ||||||||
|
leptin receptor | 0.433 | 0.808 | 0.99 |
|
disease | 0.330 | None | 1.000 | 11 | 1 | 1986 | 2018 | ||||||||
|
insulin receptor substrate 2 | 0.535 | 0.654 | 0.99 |
|
disease | 0.330 | None | 0.800 | 5 | 0 | 2010 | 2018 | ||||||||
|
Sp1 transcription factor | 0.493 | 0.769 | 1.00 |
|
disease | 0.330 | None | 1.000 | 4 | 0 | 2001 | 2019 | ||||||||
|
NAD(P)H quinone dehydrogenase 1 | 0.434 | 0.885 | 1.2E-09 |
|
disease | 0.310 | None | 1.000 | 2 | 0 | 2013 | 2018 | ||||||||
|
glutathione peroxidase 1 | 0.458 | 0.923 | 3.9E-05 |
|
disease | 0.310 | None | 1.000 | 2 | 0 | 2004 | 2010 | ||||||||
|
hydroxysteroid 11-beta dehydrogenase 1 | 0.520 | 0.731 | 0.42 |
|
disease | 0.310 | None | 1.000 | 2 | 0 | 2004 | 2017 | ||||||||
|
SIM bHLH transcription factor 1 | 0.626 | 0.654 | 1.00 |
|
disease | 0.310 | None | 0.500 | 2 | 0 | 2008 | 2019 | ||||||||
|
CD40 molecule | 0.396 | 0.846 | 0.85 |
|
disease | 0.310 | None | 1.000 | 2 | 0 | 2018 | 2018 | ||||||||
|
glucagon like peptide 1 receptor | 0.471 | 0.846 | 0.29 |
|
disease | 0.300 | None | 0.919 | 37 | 0 | 1999 | 2019 | ||||||||
|
aldo-keto reductase family 1 member B | 0.491 | 0.885 | 2.0E-05 |
|
disease | 0.300 | None | 1.000 | 28 | 0 | 1998 | 2020 |