Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.800 GeneticVariation LHGDN Effect of the p53 codon 72 and intron 3 polymorphisms on non-small cell lung cancer (NSCLC) prognosis. 18259947

2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.800 Biomarker LHGDN The extract of Hibiscus syriacus inducing apoptosis by activating p53 and AIF in human lung cancer cells. 18306460

2008
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.800 PosttranslationalModification LHGDN Quantitative p16 and ESR1 methylation in the peripheral blood of patients with non-small cell lung cancer. 18949413

2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.800 GeneticVariation LHGDN Influence of p53 codon 72 exon 4, GSTM1, GSTT1 and GSTP1*B polymorphisms in lung cancer risk in a Brazilian population. 18280004

2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.800 GeneticVariation LHGDN Etiologic value of p53 mutation spectra and differences with histology in lung cancers. 18271927

2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.800 GeneticVariation LHGDN Prognostic impact of p53 Pro72 homozygous genotype in non-small cell lung cancer patients. 18288414

2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.800 GeneticVariation LHGDN Plasma DNA, microsatellite alterations, and p53 tumor mutations are associated with disease-free survival in radically resected non-small cell lung cancer patients: a study of the perugia multidisciplinary team for thoracic oncology. 18379354

2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.800 GeneticVariation LHGDN TP53 gene mutations of lung cancer patients in upper northern Thailand and environmental risk factors. 18656689

2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.800 Biomarker LHGDN Knockdown of integrin beta4-induced autophagic cell death associated with P53 in A549 lung adenocarcinoma cells. 18959757

2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.800 GeneticVariation LHGDN Association study of TP53 polymorphisms with lung cancer in a Korean population. 18363031

2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.800 Biomarker LHGDN Epidemiology of doublet/multiplet mutations in lung cancers: evidence that a subset arises by chronocoordinate events. 19005564

2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.800 GeneticVariation LHGDN The TP53 Arg72Pro polymorphism and lung cancer risk in a population of Northern Spain. 18336951

2008
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.800 Biomarker LHGDN Retrospective analysis of the prognostic role of p16 protein inactivation in plasma in patients with locally advanced non-small cell lung cancer. 18243403

2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.800 GeneticVariation LHGDN p53 Arg72Pro polymorphism predicts survival outcome in lung cancer patients in Indian population. 18181044

2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.800 AlteredExpression LHGDN Epigenetic silencing of AXIN2/betaTrCP and deregulation of p53-mediated control lead to wild-type beta-catenin nuclear accumulation in lung tumorigenesis. 18372914

2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.800 GeneticVariation LHGDN p53 codon 72 polymorphism and HPV status in lung cancer. 18758421

2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.800 GeneticVariation LHGDN Clinical significance of the p53 pathway and associated gene therapy in non-small cell lung cancers. 17280505

2007
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.800 GeneticVariation LHGDN Patterns of EGFR, HER2, TP53, and KRAS mutations of p14arf expression in non-small cell lung cancers in relation to smoking history. 17575133

2007
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.800 Biomarker LHGDN p53 regulates cellular responses to environmental carcinogen benzo[a]pyrene-7,8-diol-9,10-epoxide in human lung cancer cells. 17630511

2007
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.800 Biomarker LHGDN Effects of exogenous p16(ink4a) gene on biological behaviors of human lung cancer cells. 17393105

2007
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.800 Biomarker LHGDN Radiosensitization dependent on p53 function in bronchial carcinoma cells by the isoflavone genistein and estradiol in vitro. 17406801

2007
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.800 Biomarker LHGDN P53 and MDM2 isoforms in blood from lung cancer patients. 17620186

2007
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.800 GeneticVariation LHGDN Clonality and prognostic implications of p53 and epidermal growth factor receptor somatic aberrations in multiple primary lung cancers. 17200338

2007
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.800 AlteredExpression LHGDN Apoptotic markers p53, Bcl-2 and Bax in primary lung cancer. 17091766

2007
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.800 AlteredExpression LHGDN Elevated p53 and p21waf1 mRNA expression in blood lymphocytes from lung cancer patients with chemoresistance. 18035504

2007