| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
fibrillin 1 | 0.417 | 0.846 | 1.00 |
|
disease | 1.000 | definitive | 0.986 | 518 | 1000 | 1973 | 2020 | ||||||||
|
transforming growth factor beta receptor 2 | 0.413 | 0.846 | 0.13 |
|
disease | 0.500 | None | 1.000 | 34 | 4 | 1994 | 2019 | ||||||||
|
latent transforming growth factor beta binding protein 2 | 0.572 | 0.692 | 7.4E-04 |
|
disease | 0.410 | limited | 1.000 | 1 | 2 | 2012 | 2012 | ||||||||
|
matrix metallopeptidase 9 | 0.305 | 0.923 | 1.9E-17 |
|
disease | 0.310 | None | 1.000 | 2 | 0 | 2008 | 2019 | ||||||||
|
matrix metallopeptidase 2 | 0.333 | 0.923 | 0.84 |
|
disease | 0.310 | None | 1.000 | 2 | 0 | 2006 | 2008 | ||||||||
|
nitric oxide synthase 2 | 0.364 | 0.923 | 4.0E-15 |
|
disease | 0.310 | None | 1.000 | 2 | 0 | 2014 | 2017 | ||||||||
|
cystathionine beta-synthase | 0.465 | 0.885 | 3.1E-05 |
|
disease | 0.310 | None | 1.000 | 2 | 0 | 2009 | 2018 | ||||||||
|
catalase | 0.359 | 0.962 | 1.6E-10 |
|
disease | 0.300 | None | 1.000 | 1 | 0 | 2014 | 2014 | ||||||||
|
superoxide dismutase 2 | 0.379 | 0.923 | 0.15 |
|
disease | 0.300 | None | 1.000 | 1 | 0 | 2014 | 2014 | ||||||||
|
superoxide dismutase 1 | 0.379 | 0.962 | 0.18 |
|
disease | 0.300 | None | 1.000 | 1 | 0 | 2014 | 2014 | ||||||||
|
laminin subunit gamma 1 | 0.628 | 0.654 | 1.00 |
|
disease | 0.300 | None | 1.000 | 1 | 0 | 2014 | 2014 | ||||||||
|
transforming growth factor beta receptor 1 | 0.451 | 0.885 | 0.85 |
|
disease | 0.200 | None | 1.000 | 17 | 1 | 2006 | 2019 | ||||||||
|
fibrillin 2 | 0.505 | 0.808 | 1.00 |
|
disease | 0.200 | None | 1.000 | 11 | 1 | 1993 | 2020 | ||||||||
|
MUS81 structure-specific endonuclease subunit | 0.686 | 0.462 | 8.8E-13 |
|
disease | 0.200 | None | 1.000 | 1 | 0 | 2007 | 2007 | ||||||||
|
transforming growth factor beta 1 | 0.287 | 0.962 | 3.7E-02 |
|
disease | 0.100 | None | 0.917 | 12 | 0 | 2003 | 2019 | ||||||||
|
elastin | 0.415 | 0.885 | 2.1E-14 |
|
disease | 0.100 | None | 1.000 | 11 | 0 | 1990 | 2019 | ||||||||
|
epidermal growth factor | 0.357 | 0.923 | 8.5E-17 |
|
disease | 0.100 | None | 1.000 | 10 | 0 | 1992 | 2013 | ||||||||
|
potassium voltage-gated channel subfamily Q member 1 | 0.485 | 0.769 | 4.5E-08 |
|
disease | 0.100 | None | 0 | 1 | |||||||||||
|
angiotensin II receptor type 1 | 0.423 | 0.846 | 5.3E-04 |
|
disease | 0.080 | None | 0.875 | 8 | 0 | 2008 | 2019 | ||||||||
|
collagen type I alpha 2 chain | 0.486 | 0.846 | 1.00 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 1985 | 1990 | ||||||||
|
angiotensinogen | 0.367 | 0.923 | 5.0E-08 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2009 | 2019 | ||||||||
|
transforming growth factor beta 2 | 0.433 | 0.885 | 1.00 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2012 | 2018 | ||||||||
|
decorin | 0.457 | 0.808 | 0.31 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 1990 | 1993 | ||||||||
|
SMAD family member 2 | 0.456 | 0.808 | 1.00 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2018 | 2019 | ||||||||
|
collagen type III alpha 1 chain | 0.477 | 0.808 | 1.00 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 1987 | 2012 |