Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.700 Biomarker CTD_human MET amplification identifies a small and aggressive subgroup of esophagogastric adenocarcinoma with evidence of responsiveness to crizotinib. 22042947

2011

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.700 Biomarker CTD_human Clinicopathologic characteristics of patients with stage III/IV (M(0)) advanced gastric cancer, according to HER2 status assessed by immunohistochemistry and fluorescence in situ hybridization. 21532492

2011

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.700 Biomarker CTD_human Prognostic implications of the expression of erbB2, topoisomerase II alpha and thymidylate synthase in metastatic gastric cancer after fluorouracil-based therapy. 15640503

2004

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.640 Biomarker CTD_human

Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.620 Biomarker CTD_human Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes. 22484628

2012

Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.620 Biomarker CTD_human Three-gene predictor of clinical outcome for gastric cancer patients treated with chemotherapy. 21173787

2012

Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.620 Biomarker CTD_human Discovery of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), a potent and selective inhibitor of the fibroblast growth factor receptor family of receptor tyrosine kinase. 21936542

2011

Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.610 Biomarker CTD_human

Entrez Id: 1316
Gene Symbol: KLF6
KLF6
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.610 Biomarker CTD_human

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 Biomarker CTD_human Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. 24816253

2014

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 Biomarker CTD_human Chronic aspirin use suppresses CDH1 methylation in human gastric mucosa. 19184424

2010

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 Biomarker CTD_human Germline CDH1 deletions in hereditary diffuse gastric cancer families. 19168852

2009

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 Biomarker CTD_human Identification of CDH1 germline missense mutations associated with functional inactivation of the E-cadherin protein in young gastric cancer probands. 12588804

2003

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 Biomarker CTD_human Germline E-cadherin gene (CDH1) mutations predispose to familial gastric cancer and colorectal cancer. 10072428

1999

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 Biomarker CTD_human E-cadherin germline mutations in familial gastric cancer. 9537325

1998

Entrez Id: 843
Gene Symbol: CASP10
CASP10
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 Biomarker CTD_human

Entrez Id: 3659
Gene Symbol: IRF1
IRF1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.600 Biomarker CTD_human

Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.580 Biomarker CTD_human Antitumor action of the MET tyrosine kinase inhibitor crizotinib (PF-02341066) in gastric cancer positive for MET amplification. 22729845

2012

Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.580 Biomarker CTD_human MET amplification identifies a small and aggressive subgroup of esophagogastric adenocarcinoma with evidence of responsiveness to crizotinib. 22042947

2011

Entrez Id: 472
Gene Symbol: ATM
ATM
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.520 Biomarker CTD_human Loss-of-function variants in ATM confer risk of gastric cancer. 26098866

2015

Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.520 Biomarker CTD_human Upregulation of heme oxygenase-1 and p21 confers resistance to apoptosis in human gastric cancer cells. 14647439

2004

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.500 Biomarker CTD_human Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. 24816253

2014

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.500 Biomarker CTD_human Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes. 22484628

2012

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.460 Biomarker CTD_human Point mutations of K-ras and H-ras genes in forestomach neoplasms from control B6C3F1 mice and following exposure to 1,3-butadiene, isoprene or chloroprene for up to 2-years. 11397402

2001

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.460 Biomarker CTD_human DNA adduct measurements, cell proliferation and tumor mutation induction in relation to tumor formation in B6C3F1 mice fed coal tar or benzo[a]pyrene. 10874023

2000