Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.210 Biomarker RGD Expression of monocyte chemoattractant protein-1 in rat dorsal root ganglia and spinal cord in experimental models of neuropathic pain. 19059387

2009

Entrez Id: 100506742
Gene Symbol: CASP12
CASP12
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Evaluation of apoptotic pathways in dorsal root ganglion neurons following peripheral nerve injury. 29659443

2018

Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Fas Ligand Gene (Faslg) Plays an Important Role in Nerve Degeneration and Regeneration After Rat Sciatic Nerve Injury. 29970988

2018

Entrez Id: 840
Gene Symbol: CASP7
CASP7
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Evaluation of apoptotic pathways in dorsal root ganglion neurons following peripheral nerve injury. 29659443

2018

Entrez Id: 494330
Gene Symbol: MIR381
MIR381
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Overexpression of miR-381 relieves neuropathic pain development via targeting HMGB1 and CXCR4. 30142543

2018

Entrez Id: 836
Gene Symbol: CASP3
CASP3
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Evaluation of apoptotic pathways in dorsal root ganglion neurons following peripheral nerve injury. 29659443

2018

Entrez Id: 841
Gene Symbol: CASP8
CASP8
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Evaluation of apoptotic pathways in dorsal root ganglion neurons following peripheral nerve injury. 29659443

2018

Entrez Id: 3920
Gene Symbol: LAMP2
LAMP2
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Therapeutic RGD Effect of autophagy on allodynia, hyperalgesia and astrocyte activation in a rat model of neuropathic pain. 30015858

2018

Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Therapeutic RGD Chinese tuina downregulates the elevated levels of tissue plasminogen activator in sciatic nerve injured Sprague-Dawley rats. 25967608

2017

Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Increased GSK-3β expression in DRG microglia in response to sciatic nerve crush. 27125978

2016

Entrez Id: 2902
Gene Symbol: GRIN1
GRIN1
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Hippocampal NMDAR-Wnt-Catenin signaling disrupted with cognitive deficits in adolescent offspring exposed to prenatal hypoxia. 26656067

2016

Entrez Id: 4035
Gene Symbol: LRP1
LRP1
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Hippocampal NMDAR-Wnt-Catenin signaling disrupted with cognitive deficits in adolescent offspring exposed to prenatal hypoxia. 26656067

2016

Entrez Id: 2904
Gene Symbol: GRIN2B
GRIN2B
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Hippocampal NMDAR-Wnt-Catenin signaling disrupted with cognitive deficits in adolescent offspring exposed to prenatal hypoxia. 26656067

2016

Entrez Id: 5859
Gene Symbol: QARS1
QARS1
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Expression profile of aminoacyl-tRNA synthetases in dorsal root ganglion neurons after peripheral nerve injury. 25467976

2015

Entrez Id: 3735
Gene Symbol: KARS1
KARS1
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Expression profile of aminoacyl-tRNA synthetases in dorsal root ganglion neurons after peripheral nerve injury. 25467976

2015

Entrez Id: 823
Gene Symbol: CAPN1
CAPN1
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Influence of electrical stimulation on calpain and ubiquitin-proteasome systems in the denervated and unloaded rat tibialis anterior muscles. 24745757

2014

Entrez Id: 824
Gene Symbol: CAPN2
CAPN2
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Influence of electrical stimulation on calpain and ubiquitin-proteasome systems in the denervated and unloaded rat tibialis anterior muscles. 24745757

2014

Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Therapeutic RGD Substrate-mediated nanoparticle/gene delivery to MSC spheroids and their applications in peripheral nerve regeneration. 24388817

2014

Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Therapeutic RGD Minocycline prevents dynorphin-induced neurotoxicity during neuropathic pain in rats. 25172308

2014

Entrez Id: 8880
Gene Symbol: FUBP1
FUBP1
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD FBP1 and p27kip1 expression after sciatic nerve injury: implications for Schwann cells proliferation and differentiation. 23939805

2014

Entrez Id: 407053
Gene Symbol: MIR96
MIR96
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Intrathecal miR-96 inhibits Nav1.3 expression and alleviates neuropathic pain in rat following chronic construction injury. 24234845

2014

Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Therapeutic RGD Pharmacological activation of heme oxygenase (HO)-1/carbon monoxide pathway prevents the development of peripheral neuropathic pain in Wistar rats. 23224421

2013

Entrez Id: 8912
Gene Symbol: CACNA1H
CACNA1H
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Upregulation of T-type Ca2+ channels in primary sensory neurons in spinal nerve injury. 22972512

2013

Entrez Id: 386724
Gene Symbol: AMIGO3
AMIGO3
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD AMIGO3 is an NgR1/p75 co-receptor signalling axon growth inhibition in the acute phase of adult central nervous system injury. 23613963

2013

Entrez Id: 8911
Gene Symbol: CACNA1I
CACNA1I
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy
0.200 Biomarker RGD Upregulation of T-type Ca2+ channels in primary sensory neurons in spinal nerve injury. 22972512

2013