| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
transforming growth factor beta 1 | 0.287 | 0.962 | 3.7E-02 |
|
disease | 0.360 | None | 1.000 | 7 | 0 | 2005 | 2020 | ||||||||
|
HtrA serine peptidase 1 | 0.532 | 0.692 | 4.9E-04 |
|
disease | 0.330 | strong | 1.000 | 4 | 1 | 2010 | 2017 | ||||||||
|
secreted protein acidic and cysteine rich | 0.445 | 0.846 | 0.89 |
|
disease | 0.330 | None | 1.000 | 3 | 0 | 2011 | 2018 | ||||||||
|
SMAD family member 3 | 0.415 | 0.923 | 0.80 |
|
disease | 0.120 | None | 1.000 | 2 | 0 | 2016 | 2017 | ||||||||
|
lamin A/C | 0.384 | 0.885 | 1.00 |
|
disease | 0.110 | None | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
disease | 0.100 | None | 1.000 | 31 | 0 | 2004 | 2019 | ||||||||
|
aggrecan | 0.528 | 0.846 | 1.00 |
|
disease | 0.100 | None | 0.962 | 26 | 0 | 2002 | 2019 | ||||||||
|
vitamin D receptor | 0.352 | 0.885 | 1.7E-05 |
|
disease | 0.100 | None | 0.875 | 24 | 2 | 1998 | 2020 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.100 | None | 1.000 | 24 | 0 | 2013 | 2019 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.100 | None | 1.000 | 10 | 3 | 2011 | 2019 | ||||||||
|
parkin RBR E3 ubiquitin protein ligase | 0.431 | 0.846 | 6.9E-07 |
|
disease | 0.100 | None | 1.000 | 1 | 1 | 2013 | 2013 | ||||||||
|
CUB and Sushi multiple domains 1 | 0.610 | 0.500 | 1.00 |
|
disease | 0.100 | None | 1.000 | 1 | 1 | 2013 | 2013 | ||||||||
|
glypican 6 | 0.626 | 0.654 | 0.14 |
|
disease | 0.100 | None | 1.000 | 1 | 1 | 2013 | 2013 | ||||||||
|
homogentisate 1,2-dioxygenase | 0.631 | 0.577 | 3.0E-08 |
|
disease | 0.100 | None | 0 | 0 | |||||||||||
|
SPG7 matrix AAA peptidase subunit, paraplegin | 0.436 | 0.885 | 2.0E-36 |
|
disease | 0.100 | None | 0 | 1 | |||||||||||
|
bone morphogenetic protein 7 | 0.498 | 0.769 | 0.13 |
|
disease | 0.090 | None | 1.000 | 9 | 0 | 2016 | 2019 | ||||||||
|
interleukin 1 alpha | 0.333 | 0.962 | 1.6E-04 |
|
disease | 0.080 | None | 1.000 | 8 | 0 | 2004 | 2019 | ||||||||
|
microRNA 21 | 0.363 | 0.846 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 2014 | 2018 | |||||||||
|
matrix metallopeptidase 3 | 0.408 | 0.885 | 5.7E-15 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 2002 | 2018 | ||||||||
|
collagen type IX alpha 3 chain | 0.569 | 0.769 | 3.3E-12 |
|
disease | 0.060 | None | 0.833 | 6 | 0 | 2002 | 2019 | ||||||||
|
matrix metallopeptidase 13 | 0.452 | 0.923 | 7.9E-18 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2017 | 2019 | ||||||||
|
SRY-box transcription factor 9 | 0.419 | 0.846 | 1.00 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2003 | 2019 | ||||||||
|
growth differentiation factor 5 | 0.511 | 0.692 | 0.67 |
|
disease | 0.050 | None | 1.000 | 5 | 1 | 2004 | 2019 | ||||||||
|
ADAM metallopeptidase with thrombospondin type 1 motif 4 | 0.582 | 0.692 | 2.0E-06 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2006 | 2019 | ||||||||
|
collagen type II alpha 1 chain | 0.444 | 0.846 | 1.00 |
|
disease | 0.050 | None | 1.000 | 5 | 3 | 2016 | 2019 |