×
Entrez Id: 3481
Gene Symbol: IGF2
IGF2
Hepatoblastoma
0.700
Biomarker
RGD
Changes in the antioxidant defense and hepatic drug metabolizing enzyme and isoenzyme levels, 8-hydroxydeoxyguanosine formation and expressions of c-raf.1 and insulin-like growth factor II genes during the stages of development of hepatocellular carcinoma in rats.
17554210 2007
×
Entrez Id: 5111
Gene Symbol: PCNA
PCNA
Hepatoblastoma
0.510
Therapeutic
RGD
Boron inhibits the proliferating cell nuclear antigen index, molybdenum containing proteins and ameliorates oxidative stress in hepatocellular carcinoma.
23219601 2013
×
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
Hepatoblastoma
0.510
Biomarker
RGD
Hepatocellular neoplasms induced by low-number pancreatic islet transplants in streptozotocin diabetic rats.
9060843 1997
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Hepatoblastoma
0.400
Biomarker
RGD
Effect of human umbilical cord blood derived CD34+ hematopoietic stem cell on the expression of Wnt4 and P53 genes in a rat model of hepatocellular carcinoma.
29429512 2018
×
Entrez Id: 2719
Gene Symbol: GPC3
GPC3
Hepatoblastoma
0.400
Therapeutic
RGD
Evaluation of antiglypican-3 therapy as a promising target for amelioration of hepatic tissue damage in hepatocellular carcinoma.
25449037 2015
×
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
Hepatoblastoma
0.270
Biomarker
RGD
Verapamil and rifampin effect on p-glycoprotein expression in hepatocellular carcinoma.
25625052 2014
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Hepatoblastoma
0.230
Biomarker
RGD
Role of HSP90, CDC37, and CRM1 as modulators of P16(INK4A) activity in rat liver carcinogenesis and human liver cancer.
16317707 2005
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Hepatoblastoma
0.230
Biomarker
RGD
De novo methylation of the p16INK4A gene in early preneoplastic liver and tumors induced by folate/methyl deficiency in rats.
12359353 2002
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Hepatoblastoma
0.230
Biomarker
RGD
Sequential changes in hepatocarcinogenesis induced by diethylnitrosamine plus thioacetamide in Fischer 344 rats: induction of gankyrin expression in liver fibrosis, pRB degradation in cirrhosis, and methylation of p16(INK4A) exon 1 in hepatocellular carcinoma.
11301474 2001
×
Entrez Id: 6927
Gene Symbol: HNF1A
HNF1A
Hepatoblastoma
0.220
Therapeutic
RGD
The HNF1α-regulated lncRNA HNF1A-AS1 reverses the malignancy of hepatocellular carcinoma by enhancing the phosphatase activity of SHP-1.
29466992 2018
×
Entrez Id: 3643
Gene Symbol: INSR
INSR
Hepatoblastoma
0.220
Biomarker
RGD
The beta secretase BACE1 regulates the expression of insulin receptor in the liver.
29610518 2018
×
Entrez Id: 3643
Gene Symbol: INSR
INSR
Hepatoblastoma
0.220
Biomarker
RGD
Mitogenic insulin receptor-A is overexpressed in human hepatocellular carcinoma due to EGFR-mediated dysregulation of RNA splicing factors.
23633480 2013
×
Entrez Id: 4609
Gene Symbol: MYC
MYC
Hepatoblastoma
0.220
Biomarker
RGD
Mechanistic study on liver tumor promoting effects of flutamide in rats.
22076107 2012
×
Entrez Id: 4609
Gene Symbol: MYC
MYC
Hepatoblastoma
0.220
Therapeutic
RGD
Antioxidant N-acetyl-L-cysteine (NAC) supplementation reduces reactive oxygen species (ROS)-mediated hepatocellular tumor promotion of indole-3-carbinol (I3C) in rats.
22129741 2011
×
Entrez Id: 983
Gene Symbol: CDK1
CDK1
Hepatoblastoma
0.220
Biomarker
RGD
Forkhead box M1B is a determinant of rat susceptibility to hepatocarcinogenesis and sustains ERK activity in human HCC.
19136513 2009
×
Entrez Id: 5465
Gene Symbol: PPARA
PPARA
Hepatoblastoma
0.220
SusceptibilityMutation
RGD
PPAR-alpha L162V polymorphism in human hepatocellular carcinoma.
19119483 2008
×
Entrez Id: 5747
Gene Symbol: PTK2
PTK2
Hepatoblastoma
0.220
Biomarker
RGD
Marked suppression of tumor growth by FTY720 in a rat liver tumor model: the significance of down-regulation of cell survival Akt pathway.
17203219 2007
×
Entrez Id: 836
Gene Symbol: CASP3
CASP3
Hepatoblastoma
0.210
Therapeutic
RGD
Chloroquine upregulates TRAIL/TRAILR2 expression and potentiates doxorubicin anti-tumor activity in thioacetamide-induced hepatocellular carcinoma model.
29133031 2018
×
Entrez Id: 355
Gene Symbol: FAS
FAS
Hepatoblastoma
0.210
Biomarker
RGD
Samsum Ant Venom Exerts Anticancer Activity Through Immunomodulation In Vitro and In Vivo.
29634416 2018
×
Entrez Id: 7015
Gene Symbol: TERT
TERT
Hepatoblastoma
0.210
Biomarker
RGD
Nuclear translocation of telomerase reverse transcriptase: a critical process in chemical induced hepatocellular carcinogenesis.
20353272 2010
×
Entrez Id: 3172
Gene Symbol: HNF4A
HNF4A
Hepatoblastoma
0.210
Biomarker
RGD
Hepatocyte nuclear factor 4 alpha suppresses the development of hepatocellular carcinoma.
20876809 2010
×
Entrez Id: 2022
Gene Symbol: ENG
ENG
Hepatoblastoma
0.210
Biomarker
RGD
Expressions of SE-1, CD31 and CD105 in the vascular endothelial cells and serum of rat with hepatocellular carcinoma.
20368095 2010
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Hepatoblastoma
0.210
Biomarker
RGD
CpG site hypermethylation of E-cadherin and Connexin26 genes in hepatocellular carcinomas induced by a choline-deficient L-Amino Acid-defined diet in rats.
17295234 2007
×
Entrez Id: 4233
Gene Symbol: MET
MET
Hepatoblastoma
0.210
Biomarker
RGD
In vivo detection of c-MET expression in a rat hepatocarcinogenesis model using molecularly targeted magnetic resonance imaging.
17311762 2007
×
Entrez Id: 19
Gene Symbol: ABCA1
ABCA1
Hepatoblastoma
0.210
Biomarker
RGD
Hypercholesterolemia in rats with hepatomas: increased oxysterols accelerate efflux but do not inhibit biosynthesis of cholesterol.
16941710 2006