Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.400 Biomarker CTD_human Genetic variation in the sex hormone metabolic pathway and endometriosis risk: an evaluation of candidate genes. 21958689

2011

Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.400 Biomarker CTD_human Steroidogenic enzyme and key decidualization marker dysregulation in endometrial stromal cells from women with versus without endometriosis. 18815356

2009

Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.330 Biomarker CTD_human Expression of AKR1B1, AKR1C3 and other genes of prostaglandin F2α biosynthesis and action in ovarian endometriosis tissue and in model cell lines. 25446850

2015

Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.330 Biomarker CTD_human Promoter methylation regulates estrogen receptor 2 in human endometrium and endometriosis. 17625110

2007

Entrez Id: 3586
Gene Symbol: IL10
IL10
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.320 Biomarker CTD_human Elevated serum chemokines are independently associated with both endometriosis and uranium exposure. 30579999

2019

Entrez Id: 5320
Gene Symbol: PLA2G2A
PLA2G2A
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.320 Biomarker CTD_human Expression of AKR1B1, AKR1C3 and other genes of prostaglandin F2α biosynthesis and action in ovarian endometriosis tissue and in model cell lines. 25446850

2015

Entrez Id: 3484
Gene Symbol: IGFBP1
IGFBP1
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.320 Biomarker CTD_human Unique transcriptome, pathways, and networks in the human endometrial fibroblast response to progesterone in endometriosis. 20864642

2011

Entrez Id: 5241
Gene Symbol: PGR
PGR
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.320 Biomarker CTD_human Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis. 21232532

2011

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.320 Biomarker CTD_human Molecular evidence for differences in endometrium in severe versus mild endometriosis. 21063030

2011

Entrez Id: 5241
Gene Symbol: PGR
PGR
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.320 Biomarker CTD_human Unique transcriptome, pathways, and networks in the human endometrial fibroblast response to progesterone in endometriosis. 20864642

2011

Entrez Id: 2516
Gene Symbol: NR5A1
NR5A1
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.320 Biomarker CTD_human Transcriptional activation of steroidogenic factor-1 by hypomethylation of the 5' CpG island in endometriosis. 17519303

2007

Entrez Id: 3164
Gene Symbol: NR4A1
NR4A1
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.310 Biomarker CTD_human Nuclear receptor, coregulator signaling, and chromatin remodeling pathways suggest involvement of the epigenome in the steroid hormone response of endometrium and abnormalities in endometriosis. 22138541

2012

Entrez Id: 3065
Gene Symbol: HDAC1
HDAC1
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.310 Biomarker CTD_human Nuclear receptor, coregulator signaling, and chromatin remodeling pathways suggest involvement of the epigenome in the steroid hormone response of endometrium and abnormalities in endometriosis. 22138541

2012

Entrez Id: 3479
Gene Symbol: IGF1
IGF1
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.310 Biomarker CTD_human Molecular evidence for differences in endometrium in severe versus mild endometriosis. 21063030

2011

Entrez Id: 5167
Gene Symbol: ENPP1
ENPP1
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.310 Biomarker CTD_human Unique transcriptome, pathways, and networks in the human endometrial fibroblast response to progesterone in endometriosis. 20864642

2011

Entrez Id: 5617
Gene Symbol: PRL
PRL
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.310 Biomarker CTD_human Prolactin and growth hormone secretion after thyrotrophin-releasing hormone infusion and dopaminergic (DA2) blockade in infertile patients with minimal/mild endometriosis. 11925390

2002

Entrez Id: 4283
Gene Symbol: CXCL9
CXCL9
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.300 Biomarker CTD_human Elevated serum chemokines are independently associated with both endometriosis and uranium exposure. 30579999

2019

Entrez Id: 6356
Gene Symbol: CCL11
CCL11
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.300 Biomarker CTD_human Elevated serum chemokines are independently associated with both endometriosis and uranium exposure. 30579999

2019

Entrez Id: 10563
Gene Symbol: CXCL13
CXCL13
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.300 Biomarker CTD_human Elevated serum chemokines are independently associated with both endometriosis and uranium exposure. 30579999

2019

Entrez Id: 6367
Gene Symbol: CCL22
CCL22
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.300 Biomarker CTD_human Elevated serum chemokines are independently associated with both endometriosis and uranium exposure. 30579999

2019

Entrez Id: 6346
Gene Symbol: CCL1
CCL1
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.300 Biomarker CTD_human Elevated serum chemokines are independently associated with both endometriosis and uranium exposure. 30579999

2019

Entrez Id: 5737
Gene Symbol: PTGFR
PTGFR
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.300 Biomarker CTD_human Expression of AKR1B1, AKR1C3 and other genes of prostaglandin F2α biosynthesis and action in ovarian endometriosis tissue and in model cell lines. 25446850

2015

Entrez Id: 231
Gene Symbol: AKR1B1
AKR1B1
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.300 Biomarker CTD_human Expression of AKR1B1, AKR1C3 and other genes of prostaglandin F2α biosynthesis and action in ovarian endometriosis tissue and in model cell lines. 25446850

2015

Entrez Id: 8644
Gene Symbol: AKR1C3
AKR1C3
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.300 Biomarker CTD_human Expression of AKR1B1, AKR1C3 and other genes of prostaglandin F2α biosynthesis and action in ovarian endometriosis tissue and in model cell lines. 25446850

2015

Entrez Id: 10257
Gene Symbol: ABCC4
ABCC4
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.300 Biomarker CTD_human Expression of AKR1B1, AKR1C3 and other genes of prostaglandin F2α biosynthesis and action in ovarian endometriosis tissue and in model cell lines. 25446850

2015