Source: PSYGENET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 875
Gene Symbol: CBS
CBS
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Selective detection of endogenous H₂S in living cells and the mouse hippocampus using a ratiometric fluorescent probe. 25070356

2014
Entrez Id: 361
Gene Symbol: AQP4
AQP4
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Aquaporin-4 knockout exacerbates corticosterone-induced depression by inhibiting astrocyte function and hippocampal neurogenesis. 24422972

2014
Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Upregulated mRNA levels of SERT, NET, MAOB, and BDNF in various brain regions of ovariectomized rats exposed to chronic aversive stimuli. 23208077

2013
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Serotonin and interleukin-6: the role of genetic polymorphisms in IFN-induced neuropsychiatric symptoms. 23571152

2013
Entrez Id: 4939
Gene Symbol: OAS2
OAS2
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Molecular signatures of peripheral blood mononuclear cells during chronic interferon-α treatment: relationship with depression and fatigue. 22152193

2012
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Early activation of p38 mitogen activated protein kinase is associated with interferon-alpha-induced depression and fatigue. 21356304

2011
Entrez Id: 51083
Gene Symbol: GAL
GAL
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Fluoxetine reverts chronic restraint stress-induced depression-like behaviour and increases neuropeptide Y and galanin expression in mice. 20816900

2011
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Interferon-gamma (+874) T/A genotypes and risk of IFN-alpha-induced depression. 21161299

2011
Entrez Id: 5319
Gene Symbol: PLA2G1B
PLA2G1B
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Phospholipase A2 and cyclooxygenase 2 genes influence the risk of interferon-alpha-induced depression by regulating polyunsaturated fatty acids levels. 20034614

2010
Entrez Id: 3060
Gene Symbol: HCRT
HCRT
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET The effect of clomipramine on wake/sleep and orexinergic expression in rats. 18562438

2009
Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Gender-specific impact of brain-derived neurotrophic factor signaling on stress-induced depression-like behavior. 19358977

2009
Entrez Id: 361
Gene Symbol: AQP4
AQP4
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Requirement of AQP4 for antidepressive efficiency of fluoxetine: implication in adult hippocampal neurogenesis. 18923397

2009
Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Chronic fluoxetine treatment induces brain region-specific upregulation of genes associated with BDNF-induced long-term potentiation. 18301726

2007
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Serotonin-1A receptor gene HTR1A variation predicts interferon-induced depression in chronic hepatitis C. 17408646

2007
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Serotonin transporter mRNA expression is decreased by lamivudine and ribavirin and increased by interferon in immune cells. 16476009

2006
Entrez Id: 3454
Gene Symbol: IFNAR1
IFNAR1
CUI: C0338715
Disease: Drug-induced depressive state
Drug-induced depressive state 		0.300 Biomarker PSYGENET Promoter polymorphisms of the interferon-alpha receptor gene and development of Interferon-induced depressive symptoms in patients with chronic hepatitis C: preliminary findings. 15990456

2005