Source: BEFREE

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 0.949 178 16 1989 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 81 5 2012 2020
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta 0.319 0.885 1.00
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 78 0 2012 2020
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta 0.322 0.885 1.00
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 77 1 2012 2020
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma 0.320 0.885 1.4E-06
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 77 2 2012 2020
Entrez Id: 23291
Gene Symbol: FBXW11
FBXW11
F-box and WD repeat domain containing 11 0.626 0.462 0.98
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 65 0 1988 2020
Entrez Id: 6910
Gene Symbol: TBX5
TBX5
T-box transcription factor 5 0.528 0.769 1.00
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 65 0 1988 2020
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 65 2 1996 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.303 0.885 1.00
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 0.967 61 1 1999 2020
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
ATP binding cassette subfamily B member 1 0.344 0.885 1.3E-05
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 0.966 59 1 1993 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2
BCL2 apoptosis regulator 0.291 0.885 0.56
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 0.981 53 0 1995 2019
Entrez Id: 836
Gene Symbol: CASP3
CASP3
caspase 3 0.351 0.923 0.10
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 45 0 2002 2020
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.320 0.923 1.00
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 44 0 2009 2020
Entrez Id: 207
Gene Symbol: AKT1
AKT1
AKT serine/threonine kinase 1 0.311 0.962 0.98
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 43 0 2012 2020
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
matrix metallopeptidase 9 0.305 0.923 1.9E-17
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 43 0 1990 2019
Entrez Id: 860
Gene Symbol: RUNX2
RUNX2
RUNX family transcription factor 2 0.437 0.846 0.95
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 41 0 2000 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 0.974 39 0 1997 2019
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
MDM2 proto-oncogene 0.362 0.846 1.00
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 0.912 34 9 1993 2019
Entrez Id: 7430
Gene Symbol: EZR
EZR
ezrin 0.476 0.808 0.18
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 0.939 33 0 2003 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
erb-b2 receptor tyrosine kinase 2 0.328 0.923 6.0E-03
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 0.906 32 2 1996 2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
hypoxia inducible factor 1 subunit alpha 0.327 0.923 0.98
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 32 0 2006 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 31 1 1995 2020
Entrez Id: 407040
Gene Symbol: MIR34A
MIR34A
microRNA 34a 0.421 0.846
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 31 0 2009 2019
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
insulin like growth factor 1 0.318 0.885 0.27
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 30 1 1993 2019
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
mitogen-activated protein kinase 1 0.330 0.923 1.00
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
disease 0.100 None 1.000 30 0 1994 2019