Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
ATP binding cassette subfamily B member 1 0.344 0.885 1.3E-05
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.540 None 0.833 1 0 2011 2019
Entrez Id: 761
Gene Symbol: CA3
CA3
carbonic anhydrase 3 0.682 0.500 1.7E-03
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.500 None 1.000 1 0 2014 2015
Entrez Id: 406906
Gene Symbol: MIR122
MIR122
microRNA 122 0.468 0.808
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.400 None 1.000 7 0 2011 2020
Entrez Id: 10
Gene Symbol: NAT2
NAT2
N-acetyltransferase 2 0.451 0.885 3.3E-06
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.400 None 1.000 4 0 2002 2019
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
cytochrome P450 family 2 subfamily E member 1 0.459 0.885 8.1E-09
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.400 None 0.889 4 0 2003 2020
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
glutathione S-transferase mu 1 0.380 0.923 2.1E-03
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.400 None 1.000 2 0 2001 2019
Entrez Id: 2875
Gene Symbol: GPT
GPT
glutamic--pyruvic transaminase 0.403 0.923 3.6E-19
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.400 None 1.000 2 0 1977 2020
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
major histocompatibility complex, class I, B 0.379 0.885 3.9E-05
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.400 None 0.900 1 0 2009 2019
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
glutathione S-transferase theta 1 0.393 0.923 1.5E-04
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.390 None 1.000 3 0 2008 2020
Entrez Id: 1555
Gene Symbol: CYP2B6
CYP2B6
cytochrome P450 family 2 subfamily B member 6 0.428 0.846 1.9E-10
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.380 None 0.889 1 0 2007 2018
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
major histocompatibility complex, class II, DR beta 1 0.333 0.923 1.1E-03
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.370 None 1.000 1 0 2010 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
nuclear factor, erythroid 2 like 2 0.357 0.885 3.6E-03
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.360 None 1.000 5 0 2008 2019
Entrez Id: 8856
Gene Symbol: NR1I2
NR1I2
nuclear receptor subfamily 1 group I member 2 0.418 0.846 7.3E-09
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.360 None 1.000 2 0 2010 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.276 0.962 0.13
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.360 None 1.000 2 0 2005 2019
Entrez Id: 1244
Gene Symbol: ABCC2
ABCC2
ATP binding cassette subfamily C member 2 0.483 0.808 5.2E-47
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.360 None 0.875 2 0 2008 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.350 None 0.818 6 0 1995 2019
Entrez Id: 2946
Gene Symbol: GSTM2
GSTM2
glutathione S-transferase mu 2 0.488 0.808 3.4E-07
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.350 None 1.000 1 0 2001 2014
Entrez Id: 3565
Gene Symbol: IL4
IL4
interleukin 4 0.332 0.962 4.7E-03
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.330 None 0.833 3 0 2005 2015
Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A
major histocompatibility complex, class I, A 0.370 0.846 1.3E-03
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.330 None 1.000 2 0 2011 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.330 None 1.000 2 0 1995 2019
Entrez Id: 213
Gene Symbol: ALB
ALB
albumin 0.317 0.962 0.64
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.330 None 1.000 2 0 2008 2019
Entrez Id: 9970
Gene Symbol: NR1I3
NR1I3
nuclear receptor subfamily 1 group I member 3 0.448 0.846 3.5E-08
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.320 None 1.000 3 0 2004 2019
Entrez Id: 1559
Gene Symbol: CYP2C9
CYP2C9
cytochrome P450 family 2 subfamily C member 9 0.506 0.885 1.3E-10
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.320 None 1.000 3 0 2004 2018
Entrez Id: 1557
Gene Symbol: CYP2C19
CYP2C19
cytochrome P450 family 2 subfamily C member 19 0.467 0.846 6.5E-20
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.320 None 1.000 2 0 2003 2018
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
glutathione S-transferase pi 1 0.383 0.923 1.4E-02
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.320 None 1.000 2 0 2011 2016