Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4849
Gene Symbol: CNOT3
CNOT3
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
0.640 SomaticCausalMutation ORPHANET We identify CNOT3 as a tumor suppressor mutated in 7 of 89 (7.9%) adult T-ALLs, and its knockdown causes tumors in a sensitized Drosophila melanogaster model. 23263491

2013

Entrez Id: 25
Gene Symbol: ABL1
ABL1
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
0.600 FusionGene ORPHANET Identification of fusion genes and characterization of transcriptome features in T-cell acute lymphoblastic leukemia. 29279377

2018

Entrez Id: 3195
Gene Symbol: TLX1
TLX1
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
0.600 FusionGene ORPHANET TLX homeodomain oncogenes mediate T cell maturation arrest in T-ALL via interaction with ETS1 and suppression of TCRα gene expression. 22516263

2012

Entrez Id: 3195
Gene Symbol: TLX1
TLX1
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
0.600 FusionGene ORPHANET Hijacking T cell differentiation: new insights in TLX function in T-ALL. 22516255

2012

Entrez Id: 6886
Gene Symbol: TAL1
TAL1
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
0.600 FusionGene ORPHANET

Entrez Id: 4602
Gene Symbol: MYB
MYB
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
0.590 FusionGene ORPHANET

Entrez Id: 8021
Gene Symbol: NUP214
NUP214
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
0.400 FusionGene ORPHANET Identification of fusion genes and characterization of transcriptome features in T-cell acute lymphoblastic leukemia. 29279377

2018

Entrez Id: 30012
Gene Symbol: TLX3
TLX3
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
0.400 FusionGene ORPHANET Hijacking T cell differentiation: new insights in TLX function in T-ALL. 22516255

2012

Entrez Id: 30012
Gene Symbol: TLX3
TLX3
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
0.400 FusionGene ORPHANET TLX homeodomain oncogenes mediate T cell maturation arrest in T-ALL via interaction with ETS1 and suppression of TCRα gene expression. 22516263

2012

Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
0.400 SomaticCausalMutation ORPHANET A comprehensive analysis of the CDKN2A gene in childhood acute lymphoblastic leukemia reveals genomic deletion, copy number neutral loss of heterozygosity, and association with specific cytogenetic subgroups. 18838613

2009

Entrez Id: 4609
Gene Symbol: MYC
MYC
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
0.400 FusionGene ORPHANET

Entrez Id: 6491
Gene Symbol: STIL
STIL
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
0.400 FusionGene ORPHANET

Entrez Id: 613
Gene Symbol: BCR
BCR
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
0.380 FusionGene ORPHANET

Entrez Id: 6418
Gene Symbol: SET
SET
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
0.370 FusionGene ORPHANET Identification of fusion genes and characterization of transcriptome features in T-cell acute lymphoblastic leukemia. 29279377

2018

Entrez Id: 8028
Gene Symbol: MLLT10
MLLT10
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
0.370 FusionGene ORPHANET The present study showed MLLT10 promiscuity in pediatric T-ALL and identified a specific MLLT10 signature within the HOXA subgroup. 23673860

2013

Entrez Id: 2322
Gene Symbol: FLT3
FLT3
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
0.370 SomaticCausalMutation ORPHANET Detection of FLT3 gene and FLT3/ITD mutation by polymerase chain reaction-single-strand conformation polymorphism in patients with acute lymphoblastic leukemia. 16234090

2005

Entrez Id: 6965
Gene Symbol: TRG
TRG
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
0.370 GeneticVariation ORPHANET

Entrez Id: 6964
Gene Symbol: TRD
TRD
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
0.360 FusionGene ORPHANET

Entrez Id: 8301
Gene Symbol: PICALM
PICALM
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
0.350 FusionGene ORPHANET

Entrez Id: 6957
Gene Symbol: TRB
TRB
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
0.330 FusionGene ORPHANET

Entrez Id: 6955
Gene Symbol: TRA
TRA
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
0.320 FusionGene ORPHANET Identification of fusion genes and characterization of transcriptome features in T-cell acute lymphoblastic leukemia. 29279377

2018

Entrez Id: 8115
Gene Symbol: TCL1A
TCL1A
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
0.310 FusionGene ORPHANET

Entrez Id: 7704
Gene Symbol: ZBTB16
ZBTB16
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
0.300 FusionGene ORPHANET Identification of fusion genes and characterization of transcriptome features in T-cell acute lymphoblastic leukemia. 29279377

2018

Entrez Id: 6297
Gene Symbol: SALL2
SALL2
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
0.300 FusionGene ORPHANET Identification of fusion genes and characterization of transcriptome features in T-cell acute lymphoblastic leukemia. 29279377

2018

Entrez Id: 3187
Gene Symbol: HNRNPH1
HNRNPH1
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
0.300 FusionGene ORPHANET In pediatric T-ALL, we have identified 2 RNA processing genes, that is, HNRNPH1/5q35 and DDX3X/Xp11.3 as new MLLT10 fusion partners. 23673860

2013