Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.320 0.923 7.9E-04
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.974 459 6 1991 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.949 331 8 1990 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.989 277 8 1993 2020
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.319 0.846 1.00
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.988 252 4 2004 2020
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.303 0.885 1.00
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.990 210 3 1997 2020
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
mutL homolog 1 0.399 0.808 3.4E-05
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.985 204 11 1993 2020
Entrez Id: 324
Gene Symbol: APC
APC
APC regulator of WNT signaling pathway 0.373 0.962 1.00
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.982 165 11 1990 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
Malignant neoplasm of colon and/or rectum
disease 0.100 None 1.000 148 2 1998 2020
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
mutS homolog 2 0.406 0.808 0.90
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.978 135 3 1993 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
Malignant neoplasm of colon and/or rectum
disease 0.100 None 1.000 125 2 2005 2020
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
CEA cell adhesion molecule 5 0.420 0.846 4.2E-10
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.984 122 0 1990 2020
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.982 109 1 1995 2020
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
thymidylate synthetase 0.425 0.846 0.72
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.981 103 1 1995 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
methylenetetrahydrofolate reductase 0.337 0.885 3.2E-10
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.914 93 4 1996 2019
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
mutY DNA glycosylase 0.521 0.769 1.3E-18
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.962 79 7 2002 2019
Entrez Id: 4513
Gene Symbol: COX2
COX2
cytochrome c oxidase subunit II 0.352 0.962
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.987 78 0 1998 2020
Entrez Id: 107075310
Gene Symbol: MTCO2P12
MTCO2P12
MT-CO2 pseudogene 12 0.368 0.962
Malignant neoplasm of colon and/or rectum
disease 0.100 None 1.000 72 0 1998 2020
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
erb-b2 receptor tyrosine kinase 2 0.328 0.923 6.0E-03
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.986 72 1 1997 2020
Entrez Id: 4360
Gene Symbol: MRC1
MRC1
mannose receptor C-type 1 0.413 0.846 0.94
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.957 69 1 1996 2020
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta 0.322 0.885 1.00
Malignant neoplasm of colon and/or rectum
disease 0.100 None 1.000 69 0 2005 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta 0.319 0.885 1.00
Malignant neoplasm of colon and/or rectum
disease 0.100 None 1.000 69 0 2005 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma 0.320 0.885 1.4E-06
Malignant neoplasm of colon and/or rectum
disease 0.100 None 1.000 68 0 2005 2019
Entrez Id: 29126
Gene Symbol: CD274
CD274
CD274 molecule 0.324 0.923 1.9E-02
Malignant neoplasm of colon and/or rectum
disease 0.100 None 1.000 58 0 2013 2020
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.320 0.923 1.00
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.982 57 0 2007 2020
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
microRNA 21 0.363 0.846
Malignant neoplasm of colon and/or rectum
disease 0.100 None 1.000 56 0 2008 2019