Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0007193
Disease: Cardiomyopathy, Dilated
Cardiomyopathy, Dilated 		0.500 Biomarker RGD The EGFR tyrosine kinase inhibitor tyrphostin AG-1478 causes hypomagnesemia and cardiac dysfunction. 22646904

2012
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.500 Biomarker RGD Control of the epidermal growth factor receptor and its ligands during renal injury. 11340354

2001
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0007120
Disease: Bronchioloalveolar Adenocarcinoma
Bronchioloalveolar Adenocarcinoma 		0.400 Biomarker RGD Kras, Egfr, and Tp53 Mutations in B6C3F1/N Mouse and F344/NTac Rat Alveolar/Bronchiolar Carcinomas Resulting from Chronic Inhalation Exposure to Cobalt Metal. 26059825

2015
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.360 Biomarker RGD Enhanced expression of EGF receptor in a model of salt-sensitive hypertension. 15827348

2005
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0004096
Disease: Asthma
Asthma 		0.300 Biomarker RGD EGFR is involved in airway inflammation of asthmatic rats. 19954006

2009
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.290 Biomarker RGD Elevated transforming growth factor-alpha levels in bronchoalveolar lavage fluid of patients with acute respiratory distress syndrome. 9700116

1998
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.290 Biomarker RGD Expression of transforming growth factor-alpha and epidermal growth factor receptor is increased following bleomycin-induced lung injury in rats. 7524566

1994
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		0.280 Biomarker RGD Characteristic comparison of three rat models induced by cigarette smoke or combined with LPS: to establish a suitable model for study of airway mucus hypersecretion in chronic obstructive pulmonary disease. 22732689

2012
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0020507
Disease: Hyperplasia
Hyperplasia 		0.280 Biomarker RGD In conclusion, ADAM17 activation is involved in epidermal growth factor receptor activation and subsequent neointimal hyperplasia after vascular injury. 21357274

2011
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		0.220 Biomarker RGD Decreased autophosphorylation of EGF receptor in insulin-deficient diabetic rats. 2833110

1988
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0021368
Disease: Inflammation
Inflammation 		0.200 Biomarker RGD Inhibition of EGFR/MAPK signaling reduces microglial inflammatory response and the associated secondary damage in rats after spinal cord injury. 22824323

2012
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental 		0.200 Biomarker RGD Impaired epithelial wound healing and EGFR signaling pathways in the corneas of diabetic rats. 21330660

2011
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0242422
Disease: Parkinsonian Disorders
Parkinsonian Disorders 		0.200 Biomarker RGD Influences of dopaminergic lesion on epidermal growth factor-ErbB signals in Parkinson's disease and its model: neurotrophic implication in nigrostriatal neurons. 15857400

2005
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy 		0.200 Biomarker RGD These results suggests that EGFR-mediated ERK activation is critically important for LVH in young SHR. 12624003

2003
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0014869
Disease: Peptic Esophagitis
Peptic Esophagitis 		0.200 Biomarker RGD Increased expression of epidermal growth factor receptors in basal cell hyperplasia of the oesophagus after acid reflux oesophagitis in rats. 11966524

2002