Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1280
Gene Symbol: COL2A1
COL2A1
collagen type II alpha 1 chain 0.444 0.846 1.00
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.500 None 0.941 68 5 1993 2020
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.287 0.962 3.7E-02
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.500 None 1.000 50 3 2000 2020
Entrez Id: 1311
Gene Symbol: COMP
COMP
cartilage oligomeric matrix protein 0.503 0.808 1.3E-09
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.500 None 0.971 34 3 1995 2019
Entrez Id: 4148
Gene Symbol: MATN3
MATN3
matrilin 3 0.644 0.385 1.4E-08
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.500 None 1.000 12 1 2002 2018
Entrez Id: 1800
Gene Symbol: DPEP1
DPEP1
dipeptidase 1 0.570 0.654 3.5E-10
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.420 None 1.000 3 1 2017 2019
Entrez Id: 8854
Gene Symbol: ALDH1A2
ALDH1A2
aldehyde dehydrogenase 1 family member A2 0.578 0.692 0.36
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.420 None 1.000 3 3 2014 2018
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.276 0.962 0.13
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.400 None 0.997 381 4 1992 2020
Entrez Id: 8200
Gene Symbol: GDF5
GDF5
growth differentiation factor 5 0.511 0.692 0.67
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.400 None 0.960 50 2 2007 2019
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
SMAD family member 3 0.415 0.923 0.80
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.400 None 0.969 32 8 2003 2019
Entrez Id: 54829
Gene Symbol: ASPN
ASPN
asporin 0.636 0.500 1.0E-07
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.400 None 0.931 29 1 2005 2019
Entrez Id: 860
Gene Symbol: RUNX2
RUNX2
RUNX family transcription factor 2 0.437 0.846 0.95
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.400 None 1.000 28 0 2008 2020
Entrez Id: 2487
Gene Symbol: FRZB
FRZB
frizzled related protein 0.573 0.654 1.1E-03
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.400 None 0.923 26 2 1998 2019
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
peroxisome proliferator activated receptor gamma 0.358 0.885 2.9E-02
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.400 None 1.000 15 2 2002 2019
Entrez Id: 177
Gene Symbol: AGER
AGER
advanced glycosylation end-product specific receptor 0.420 0.885 6.4E-16
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.400 None 1.000 11 1 2005 2019
Entrez Id: 1513
Gene Symbol: CTSK
CTSK
cathepsin K 0.497 0.808 3.1E-05
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.390 None 1.000 9 0 2002 2019
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
superoxide dismutase 2 0.379 0.923 0.15
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.380 None 0.900 10 0 2004 2020
Entrez Id: 8817
Gene Symbol: FGF18
FGF18
fibroblast growth factor 18 0.647 0.577 0.39
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.370 None 1.000 7 0 2016 2019
Entrez Id: 796
Gene Symbol: CALCA
CALCA
calcitonin related polypeptide alpha 0.416 0.923 1.6E-02
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.360 None 0.857 7 0 2007 2018
Entrez Id: 1116
Gene Symbol: CHI3L1
CHI3L1
chitinase 3 like 1 0.419 0.885 1.1E-05
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.350 None 1.000 6 0 1993 2019
Entrez Id: 7052
Gene Symbol: TGM2
TGM2
transglutaminase 2 0.445 0.808 6.8E-18
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.350 None 1.000 6 0 2008 2017
Entrez Id: 59341
Gene Symbol: TRPV4
TRPV4
transient receptor potential cation channel subfamily V member 4 0.457 0.808 2.2E-16
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.340 None 1.000 5 0 2011 2019
Entrez Id: 1191
Gene Symbol: CLU
CLU
clusterin 0.426 0.885 7.8E-05
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.330 None 1.000 5 0 2006 2019
Entrez Id: 2920
Gene Symbol: CXCL2
CXCL2
C-X-C motif chemokine ligand 2 0.513 0.885 3.6E-07
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.330 None 1.000 3 0 2004 2014
Entrez Id: 6275
Gene Symbol: S100A4
S100A4
S100 calcium binding protein A4 0.448 0.769 6.2E-03
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.330 None 1.000 3 0 2006 2007
Entrez Id: 7431
Gene Symbol: VIM
VIM
vimentin 0.372 0.846 0.71
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
disease 0.320 None 1.000 4 0 2006 2019