Source: ALL
| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
age-related maculopathy susceptibility 2 | 0.670 | 0.308 | 5.2E-04 |
|
disease | 0.700 | limited | 0.951 | 182 | 8 | 2005 | 2019 | ||||||||
|
ATP binding cassette subfamily A member 4 | 0.493 | 0.769 | 5.3E-48 |
|
disease | 0.700 | strong | 0.957 | 70 | 7 | 1997 | 2019 | ||||||||
|
complement factor B | 0.532 | 0.769 | 4.7E-16 |
|
disease | 0.700 | limited | 0.966 | 58 | 12 | 2006 | 2019 | ||||||||
|
complement C3 | 0.445 | 0.885 | 0.90 |
|
disease | 0.700 | limited | 1.000 | 36 | 12 | 2007 | 2020 | ||||||||
|
complement C2 | 0.617 | 0.692 | 1.3E-16 |
|
disease | 0.680 | limited | 1.000 | 13 | 9 | 2006 | 2018 | ||||||||
|
complement factor H | 0.441 | 0.885 | 0.86 |
|
disease | 0.500 | None | 0.961 | 486 | 85 | 2005 | 2019 | ||||||||
|
HtrA serine peptidase 1 | 0.532 | 0.692 | 4.9E-04 |
|
disease | 0.500 | limited | 0.940 | 133 | 12 | 2006 | 2019 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
disease | 0.500 | None | 0.902 | 61 | 4 | 1998 | 2019 | ||||||||
|
complement factor I | 0.569 | 0.731 | 3.5E-08 |
|
disease | 0.500 | None | 0.960 | 25 | 4 | 2009 | 2019 | ||||||||
|
TIMP metallopeptidase inhibitor 3 | 0.445 | 0.923 | 0.63 |
|
disease | 0.500 | None | 0.905 | 21 | 0 | 1997 | 2019 | ||||||||
|
complement factor H related 3 | 0.663 | 0.462 | 1.7E-11 |
|
disease | 0.500 | moderate | 1.000 | 17 | 2 | 2006 | 2019 | ||||||||
|
complement factor H related 1 | 0.588 | 0.615 | 2.6E-08 |
|
disease | 0.500 | moderate | 1.000 | 16 | 4 | 2006 | 2017 | ||||||||
|
hemicentin 1 | 0.736 | 0.577 | 3.6E-38 |
|
disease | 0.500 | limited | 0.846 | 13 | 1 | 2003 | 2015 | ||||||||
|
retinitis pigmentosa GTPase regulator | 0.536 | 0.692 | 1.00 |
|
disease | 0.430 | None | 1.000 | 3 | 0 | 2002 | 2019 | ||||||||
|
complement factor H related 4 | 0.839 | 0.346 | 2.4E-18 |
|
disease | 0.420 | moderate | 1.000 | 8 | 12 | 2008 | 2018 | ||||||||
|
solute carrier family 16 member 8 | 0.760 | 0.231 | 9.0E-03 |
|
disease | 0.420 | None | 1.000 | 4 | 1 | 2013 | 2018 | ||||||||
|
complement C9 | 0.619 | 0.692 | 1.6E-24 |
|
disease | 0.420 | None | 1.000 | 4 | 4 | 2013 | 2018 | ||||||||
|
complement factor H related 2 | 0.769 | 0.346 | 1.5E-08 |
|
disease | 0.410 | limited | 1.000 | 2 | 4 | 2008 | 2013 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
disease | 0.400 | None | 0.971 | 174 | 12 | 2000 | 2020 | ||||||||
|
retinaldehyde binding protein 1 | 0.644 | 0.500 | 1.1E-05 |
|
disease | 0.400 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
retina and anterior neural fold homeobox 2 | 0.780 | 0.192 | 8.3E-03 |
|
disease | 0.400 | strong | 0 | 0 | |||||||||||
|
toll like receptor 4 | 0.321 | 0.962 | 4.6E-09 |
|
disease | 0.370 | None | 0.571 | 7 | 4 | 2005 | 2019 | ||||||||
|
C1q and TNF related 5 | 0.663 | 0.346 | 0.84 |
|
disease | 0.370 | None | 1.000 | 7 | 1 | 2003 | 2018 | ||||||||
|
fibulin 5 | 0.546 | 0.692 | 1.00 |
|
disease | 0.370 | limited | 0.857 | 7 | 5 | 2004 | 2016 | ||||||||
|
sequestosome 1 | 0.428 | 0.885 | 8.6E-04 |
|
disease | 0.340 | None | 1.000 | 5 | 0 | 2013 | 2019 |