| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.400 | None | 0.950 | 20 | 1 | 1996 | 2018 | ||||||||
|
protein C, inactivator of coagulation factors Va and VIIIa | 0.504 | 0.808 | 1.9E-05 |
|
disease | 0.400 | None | 1.000 | 15 | 1 | 2002 | 2017 | ||||||||
|
interleukin 10 | 0.281 | 0.923 | 5.9E-03 |
|
disease | 0.400 | None | 0.909 | 11 | 0 | 2001 | 2018 | ||||||||
|
toll like receptor 4 | 0.321 | 0.962 | 4.6E-09 |
|
disease | 0.370 | None | 0.875 | 8 | 1 | 2004 | 2018 | ||||||||
|
lymphotoxin alpha | 0.434 | 0.885 | 0.20 |
|
disease | 0.360 | None | 0.857 | 7 | 0 | 1999 | 2012 | ||||||||
|
high mobility group box 1 | 0.368 | 0.923 | 0.82 |
|
disease | 0.340 | None | 1.000 | 6 | 1 | 2009 | 2017 | ||||||||
|
angiopoietin 1 | 0.446 | 0.808 | 0.95 |
|
disease | 0.320 | None | 1.000 | 3 | 0 | 2005 | 2019 | ||||||||
|
lipopolysaccharide binding protein | 0.525 | 0.808 | 4.2E-15 |
|
disease | 0.310 | None | 1.000 | 2 | 0 | 2009 | 2012 | ||||||||
|
caspase 3 | 0.351 | 0.923 | 0.10 |
|
disease | 0.310 | None | 1.000 | 2 | 0 | 2005 | 2018 | ||||||||
|
nitric oxide synthase 3 | 0.378 | 0.885 | 6.7E-07 |
|
disease | 0.310 | None | 1.000 | 2 | 1 | 2010 | 2011 | ||||||||
|
transforming growth factor beta 1 | 0.287 | 0.962 | 3.7E-02 |
|
disease | 0.310 | None | 1.000 | 2 | 0 | 2005 | 2010 | ||||||||
|
nitric oxide synthase 2 | 0.364 | 0.923 | 4.0E-15 |
|
disease | 0.300 | None | 1.000 | 2 | 0 | 2007 | 2010 | ||||||||
|
interferon gamma | 0.288 | 0.962 | 0.47 |
|
disease | 0.300 | None | 1.000 | 1 | 0 | 1998 | 1998 | ||||||||
|
C-X-C motif chemokine receptor 2 | 0.445 | 0.923 | 1.4E-02 |
|
disease | 0.300 | None | 1.000 | 1 | 0 | 2007 | 2007 | ||||||||
|
mitogen-activated protein kinase 1 | 0.330 | 0.923 | 1.00 |
|
disease | 0.300 | None | 1.000 | 1 | 0 | 2004 | 2004 | ||||||||
|
transforming growth factor beta induced | 0.484 | 0.769 | 6.0E-08 |
|
disease | 0.300 | None | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
colony stimulating factor 3 | 0.377 | 0.885 | 0.38 |
|
disease | 0.300 | None | 1.000 | 1 | 0 | 2007 | 2007 | ||||||||
|
macrophage migration inhibitory factor | 0.412 | 0.885 | 1.2E-02 |
|
disease | 0.300 | None | 1.000 | 1 | 0 | 1999 | 1999 | ||||||||
|
adenosine A2b receptor | 0.617 | 0.692 | 1.8E-05 |
|
disease | 0.300 | None | 1.000 | 1 | 0 | 2016 | 2016 | ||||||||
|
adenosine A2a receptor | 0.526 | 0.769 | 0.60 |
|
disease | 0.300 | None | 1.000 | 1 | 0 | 2016 | 2016 | ||||||||
|
matrix metallopeptidase 9 | 0.305 | 0.923 | 1.9E-17 |
|
disease | 0.300 | None | 1.000 | 1 | 0 | 2005 | 2005 | ||||||||
|
adrenomedullin | 0.436 | 0.808 | 4.1E-02 |
|
disease | 0.300 | None | 1.000 | 1 | 0 | 2004 | 2004 | ||||||||
|
mitogen-activated protein kinase 3 | 0.379 | 0.885 | 3.7E-02 |
|
disease | 0.300 | None | 1.000 | 1 | 0 | 2004 | 2004 | ||||||||
|
interferon alpha 2 | 0.442 | 0.885 |
|
disease | 0.300 | None | 1.000 | 1 | 0 | 1987 | 1987 | |||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.100 | None | 0.900 | 10 | 2 | 2002 | 2019 |