| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
homeostatic iron regulator | 0.436 | 0.846 | 2.6E-08 |
|
disease | 0.900 | None | 0.979 | 385 | 23 | 1987 | 2019 | ||||||||
|
hemojuvelin BMP co-receptor | 0.621 | 0.654 | 4.2E-03 |
|
disease | 0.400 | None | 0.950 | 20 | 1 | 2005 | 2019 | ||||||||
|
bone morphogenetic protein 2 | 0.432 | 0.846 | 0.99 |
|
disease | 0.310 | strong | 1.000 | 2 | 0 | 2017 | 2019 | ||||||||
|
hepcidin antimicrobial peptide | 0.433 | 0.846 | 8.2E-03 |
|
disease | 0.200 | None | 0.970 | 66 | 1 | 2002 | 2019 | ||||||||
|
transferrin | 0.527 | 0.846 | 4.1E-08 |
|
disease | 0.130 | None | 1.000 | 4 | 2 | 2005 | 2015 | ||||||||
|
transferrin receptor 2 | 0.585 | 0.615 | 1.3E-09 |
|
disease | 0.100 | None | 1.000 | 32 | 6 | 2000 | 2017 | ||||||||
|
transferrin receptor | 0.437 | 0.885 | 7.0E-05 |
|
disease | 0.100 | None | 0.889 | 18 | 2 | 1994 | 2014 | ||||||||
|
major histocompatibility complex, class I, A | 0.370 | 0.846 | 1.3E-03 |
|
disease | 0.100 | None | 0.944 | 18 | 2 | 1980 | 2014 | ||||||||
|
solute carrier family 40 member 1 | 0.570 | 0.731 | 0.99 |
|
disease | 0.100 | None | 1.000 | 13 | 4 | 2003 | 2019 | ||||||||
|
major histocompatibility complex, class I, H (pseudogene) | 0.736 | 0.500 |
|
disease | 0.090 | None | 1.000 | 9 | 0 | 1997 | 1997 | |||||||||
|
transmembrane serine protease 6 | 0.584 | 0.654 | 4.1E-10 |
|
disease | 0.060 | None | 1.000 | 6 | 5 | 2011 | 2019 | ||||||||
|
solute carrier family 11 member 2 | 0.566 | 0.769 | 6.7E-03 |
|
disease | 0.050 | None | 0.800 | 5 | 1 | 1998 | 2014 | ||||||||
|
bone morphogenetic protein 6 | 0.531 | 0.808 | 0.76 |
|
disease | 0.050 | None | 0.600 | 5 | 0 | 2009 | 2019 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 1992 | 2010 | ||||||||
|
cytochrome b reductase 1 | 0.729 | 0.269 | 1.2E-02 |
|
disease | 0.030 | None | 1.000 | 3 | 1 | 2003 | 2017 | ||||||||
|
ceruloplasmin | 0.466 | 0.846 | 4.2E-10 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2003 | 2011 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2003 | 2015 | ||||||||
|
major histocompatibility complex, class I, B | 0.379 | 0.885 | 3.9E-05 |
|
disease | 0.020 | None | 0.500 | 2 | 0 | 1986 | 1993 | ||||||||
|
major histocompatibility complex, class I, F | 0.631 | 0.654 | 3.3E-05 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 1995 | 1997 | ||||||||
|
ubiquitin conjugating enzyme E2 D1 | 0.700 | 0.385 | 0.12 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 1998 | 2001 | ||||||||
|
succinate receptor 1 | 0.647 | 0.577 | 7.7E-04 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2011 | 2016 | ||||||||
|
beta-2-microglobulin | 0.447 | 0.846 | 0.56 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 1998 | 2013 | ||||||||
|
glyceronephosphate O-acyltransferase | 0.663 | 0.462 | 0.30 |
|
disease | 0.020 | None | 0.500 | 2 | 1 | 2017 | 2017 | ||||||||
|
glutathione S-transferase pi 1 | 0.383 | 0.923 | 1.4E-02 |
|
disease | 0.020 | None | 1.000 | 2 | 1 | 2015 | 2015 | ||||||||
|
ferritin light chain | 0.559 | 0.692 | 1.7E-09 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2007 | 2014 |