Source: ALL

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		KRAS proto-oncogene, GTPase 0.320 0.923 7.9E-04
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
Secondary malignant neoplasm of colon and/or rectum 		disease 0.100 None 0.980 492 4 2007 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		epidermal growth factor receptor 0.295 0.885 0.37
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
Secondary malignant neoplasm of colon and/or rectum 		disease 0.100 None 0.983 353 4 2003 2020
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		B-Raf proto-oncogene, serine/threonine kinase 0.319 0.846 1.00
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
Secondary malignant neoplasm of colon and/or rectum 		disease 0.100 None 0.993 145 2 2008 2020
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
Secondary malignant neoplasm of colon and/or rectum 		disease 0.100 None 1.000 69 0 2004 2020
Entrez Id: 7055
Gene Symbol: THAS
THAS 		thoracoabdominal syndrome 0.560 0.808
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
Secondary malignant neoplasm of colon and/or rectum 		disease 0.100 None 0.929 42 0 2012 2020
Entrez Id: 54658
Gene Symbol: UGT1A1
UGT1A1 		UDP glucuronosyltransferase family 1 member A1 0.464 0.769 3.3E-06
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
Secondary malignant neoplasm of colon and/or rectum 		disease 0.100 None 1.000 40 1 2004 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
Secondary malignant neoplasm of colon and/or rectum 		disease 0.100 None 0.971 35 1 2009 2019
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		NRAS proto-oncogene, GTPase 0.390 0.808 0.49
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
Secondary malignant neoplasm of colon and/or rectum 		disease 0.100 None 1.000 34 2 2011 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		erb-b2 receptor tyrosine kinase 2 0.328 0.923 6.0E-03
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
Secondary malignant neoplasm of colon and/or rectum 		disease 0.100 None 1.000 25 1 2013 2020
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5 		CEA cell adhesion molecule 5 0.420 0.846 4.2E-10
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
Secondary malignant neoplasm of colon and/or rectum 		disease 0.100 None 1.000 25 0 2011 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		phosphatase and tensin homolog 0.305 0.923 0.26
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
Secondary malignant neoplasm of colon and/or rectum 		disease 0.100 None 1.000 18 0 2007 2016
Entrez Id: 326342
Gene Symbol: ADGRE4P
ADGRE4P 		adhesion G protein-coupled receptor E4, pseudogene 0.780 0.231
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
Secondary malignant neoplasm of colon and/or rectum 		disease 0.100 None 1.000 17 0 2015 2019
Entrez Id: 79947
Gene Symbol: DHDDS
DHDDS 		dehydrodolichyl diphosphate synthase subunit 0.468 0.885 0.25
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
Secondary malignant neoplasm of colon and/or rectum 		disease 0.100 None 0.875 16 0 1998 2018
Entrez Id: 56994
Gene Symbol: CHPT1
CHPT1 		choline phosphotransferase 1 0.474 0.846 2.4E-04
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
Secondary malignant neoplasm of colon and/or rectum 		disease 0.100 None 0.875 16 0 1998 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53 		tumor protein p53 0.236 0.962 0.53
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
Secondary malignant neoplasm of colon and/or rectum 		disease 0.100 None 0.933 15 1 2001 2020
Entrez Id: 7298
Gene Symbol: TYMS
TYMS 		thymidylate synthetase 0.425 0.846 0.72
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
Secondary malignant neoplasm of colon and/or rectum 		disease 0.100 None 1.000 14 0 2002 2019
Entrez Id: 5670
Gene Symbol: PSG2
PSG2 		pregnancy specific beta-1-glycoprotein 2 0.492 0.731 1.4E-30
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
Secondary malignant neoplasm of colon and/or rectum 		disease 0.100 None 1.000 12 0 2013 2019
Entrez Id: 1087
Gene Symbol: CEACAM7
CEACAM7 		CEA cell adhesion molecule 7 0.494 0.769 1.3E-07
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
Secondary malignant neoplasm of colon and/or rectum 		disease 0.100 None 1.000 12 0 2013 2019
Entrez Id: 1084
Gene Symbol: CEACAM3
CEACAM3 		CEA cell adhesion molecule 3 0.494 0.731 1.1E-09
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
Secondary malignant neoplasm of colon and/or rectum 		disease 0.100 None 1.000 12 0 2013 2019
Entrez Id: 22806
Gene Symbol: IKZF3
IKZF3 		IKAROS family zinc finger 3 0.608 0.692 0.98
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
Secondary malignant neoplasm of colon and/or rectum 		disease 0.100 None 1.000 12 0 2011 2018
Entrez Id: 2214
Gene Symbol: FCGR3A
FCGR3A 		Fc fragment of IgG receptor IIIa 0.432 0.962 3.7E-06
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
Secondary malignant neoplasm of colon and/or rectum 		disease 0.100 None 0.750 12 0 2007 2019
Entrez Id: 2069
Gene Symbol: EREG
EREG 		epiregulin 0.554 0.692 1.2E-05
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
Secondary malignant neoplasm of colon and/or rectum 		disease 0.100 None 1.000 12 0 2007 2019
Entrez Id: 1950
Gene Symbol: EGF
EGF 		epidermal growth factor 0.357 0.923 8.5E-17
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
Secondary malignant neoplasm of colon and/or rectum 		disease 0.100 None 1.000 11 0 2008 2019
Entrez Id: 374
Gene Symbol: AREG
AREG 		amphiregulin 0.487 0.769 0.35
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
Secondary malignant neoplasm of colon and/or rectum 		disease 0.100 None 1.000 11 0 2007 2019
Entrez Id: 4255
Gene Symbol: MGMT
MGMT 		O-6-methylguanine-DNA methyltransferase 0.412 0.885 1.2E-07
CUI: C4721579
Disease: Secondary malignant neoplasm of colon and/or rectum
Secondary malignant neoplasm of colon and/or rectum 		disease 0.100 None 1.000 10 0 2010 2020