DisGeNET - a database of gene-disease associations

Source: ANIMAL_MODELS

Disease: Alzheimer's Disease ×

Gene: CASP3 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	836
Gene Symbol:	CASP3

CASP3

CUI:	C0002395
Disease:	Alzheimer's Disease

Alzheimer's Disease

0.600

Therapeutic

RGD

CART peptide activates the Nrf2/HO-1 antioxidant pathway and protects hippocampal neurons in a rat model of Alzheimer's disease.

29777699

2018

Entrez Id:	836
Gene Symbol:	CASP3

CASP3

CUI:	C0002395
Disease:	Alzheimer's Disease

Alzheimer's Disease

0.600

Therapeutic

RGD

Bajijiasu Ameliorates β-Amyloid-Triggered Endoplasmic Reticulum Stress and Related Pathologies in an Alzheimer's Disease Model.

29587274

2018

Entrez Id:	836
Gene Symbol:	CASP3

CASP3

CUI:	C0002395
Disease:	Alzheimer's Disease

Alzheimer's Disease

0.600

Therapeutic

RGD

Effects of Lignans from Schisandra chinensis Rattan Stems against Aβ

29642617

2018