Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4010
Gene Symbol: LMX1B
LMX1B
CUI: C0027341
Disease: Nail-Patella Syndrome
Nail-Patella Syndrome 		1.000 Biomarker MGD Lmx1b is required for murine trabecular meshwork formation and for maintenance of corneal transparency. 20568247

2010
Entrez Id: 4010
Gene Symbol: LMX1B
LMX1B
CUI: C0027341
Disease: Nail-Patella Syndrome
Nail-Patella Syndrome 		1.000 Biomarker MGD Lmx1b is essential for Fgf8 and Wnt1 expression in the isthmic organizer during tectum and cerebellum development in mice. 17166916

2007
Entrez Id: 4010
Gene Symbol: LMX1B
LMX1B
CUI: C0027341
Disease: Nail-Patella Syndrome
Nail-Patella Syndrome 		1.000 Biomarker MGD The pattern of Lmx1b expression during the development of the limb, eye and kidney correlates with the NPS phenotype. 15562281

2005
Entrez Id: 4010
Gene Symbol: LMX1B
LMX1B
CUI: C0027341
Disease: Nail-Patella Syndrome
Nail-Patella Syndrome 		1.000 Biomarker MGD Taken together, our studies suggest a developmental etiology for glaucoma in NPS patients and highlight lmx1b as an essential regulator of anterior segment morphogenesis and patterning. genesis 26:15-25, 2000. 10660670

2000
Entrez Id: 4010
Gene Symbol: LMX1B
LMX1B
CUI: C0027341
Disease: Nail-Patella Syndrome
Nail-Patella Syndrome 		1.000 Biomarker MGD Our results demonstrate an essential function for Lmx1b in mouse limb and kidney development and suggest that NPS might result from mutations in the human LMX1B gene. 9590288

1998
Entrez Id: 4010
Gene Symbol: LMX1B
LMX1B
CUI: C0027341
Disease: Nail-Patella Syndrome
Nail-Patella Syndrome 		1.000 Biomarker MGD Multiple calvarial defects in lmx1b mutant mice. 9664684

1998