Source: BEFREE

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3717
Gene Symbol: JAK2
JAK2 		Janus kinase 2 0.385 0.885 0.65
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		disease 1.000 None 0.968 327 5 2005 2020
Entrez Id: 4352
Gene Symbol: MPL
MPL 		MPL proto-oncogene, thrombopoietin receptor 0.510 0.692 4.1E-09
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		disease 1.000 None 0.978 86 3 1995 2020
Entrez Id: 811
Gene Symbol: CALR
CALR 		calreticulin 0.413 0.923 0.89
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		disease 0.800 limited 0.929 97 0 2013 2020
Entrez Id: 54790
Gene Symbol: TET2
TET2 		tet methylcytosine dioxygenase 2 0.458 0.808 4.3E-54
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		disease 0.500 None 0.909 10 0 2009 2019
Entrez Id: 2146
Gene Symbol: EZH2
EZH2 		enhancer of zeste 2 polycomb repressive complex 2 subunit 0.376 0.885 1.00
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		disease 0.350 None 1.000 5 1 2010 2019
Entrez Id: 2623
Gene Symbol: GATA1
GATA1 		GATA binding protein 1 0.483 0.808 0.95
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		disease 0.290 None 1.000 9 0 2001 2020
Entrez Id: 4602
Gene Symbol: MYB
MYB 		MYB proto-oncogene, transcription factor 0.490 0.692 0.82
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		disease 0.220 None 1.000 2 0 2007 2015
Entrez Id: 7157
Gene Symbol: TP53
TP53 		tumor protein p53 0.236 0.962 0.53
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		disease 0.150 None 1.000 5 4 2008 2019
Entrez Id: 23218
Gene Symbol: NBEAL2
NBEAL2 		neurobeachin like 2 0.617 0.769 6.0E-02
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		disease 0.120 None 1.000 2 0 2014 2019
Entrez Id: 80739
Gene Symbol: MPIG6B
MPIG6B 		megakaryocyte and platelet inhibitory receptor G6b 0.695 0.500 1.1E-06
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		disease 0.120 None 1.000 2 0 2018 2018
Entrez Id: 25
Gene Symbol: ABL1
ABL1 		ABL proto-oncogene 1, non-receptor tyrosine kinase 0.432 0.923 1.00
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		disease 0.100 None 1.000 41 0 1995 2019
Entrez Id: 3716
Gene Symbol: JAK1
JAK1 		Janus kinase 1 0.474 0.769 1.00
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		disease 0.100 None 0.976 41 0 2012 2020
Entrez Id: 947
Gene Symbol: CD34
CD34 		CD34 molecule 0.368 0.808 5.0E-06
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		disease 0.100 None 1.000 27 0 1993 2019
Entrez Id: 613
Gene Symbol: BCR
BCR 		BCR activator of RhoGEF and GTPase 0.431 0.885 0.99
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		disease 0.100 None 1.000 26 0 1992 2019
Entrez Id: 171023
Gene Symbol: ASXL1
ASXL1 		ASXL transcriptional regulator 1 0.482 0.808 1.3E-14
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		disease 0.100 None 0.957 23 0 2011 2019
Entrez Id: 7066
Gene Symbol: THPO
THPO 		thrombopoietin 0.513 0.692 0.20
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		disease 0.100 None 1.000 16 0 1997 2020
Entrez Id: 6646
Gene Symbol: SOAT1
SOAT1 		sterol O-acyltransferase 1 0.424 0.846 7.4E-10
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		disease 0.100 None 1.000 15 0 2007 2019
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		transforming growth factor beta 1 0.287 0.962 3.7E-02
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		disease 0.100 None 1.000 12 0 2002 2018
Entrez Id: 6427
Gene Symbol: SRSF2
SRSF2 		serine and arginine rich splicing factor 2 0.561 0.731 0.48
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		disease 0.100 None 0.900 10 0 2012 2019
Entrez Id: 6776
Gene Symbol: STAT5A
STAT5A 		signal transducer and activator of transcription 5A 0.445 0.808 1.00
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		disease 0.100 None 0.900 10 0 2007 2019
Entrez Id: 6777
Gene Symbol: STAT5B
STAT5B 		signal transducer and activator of transcription 5B 0.442 0.808 1.00
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		disease 0.090 None 0.889 9 0 2007 2019
Entrez Id: 3417
Gene Symbol: IDH1
IDH1 		isocitrate dehydrogenase (NADP(+)) 1 0.424 0.808 2.6E-12
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		disease 0.080 None 0.875 8 1 2010 2018
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		isocitrate dehydrogenase (NADP(+)) 2 0.434 0.808 0.88
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		disease 0.070 None 0.857 7 2 2010 2017
Entrez Id: 57126
Gene Symbol: CD177
CD177 		CD177 molecule 0.595 0.654
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		disease 0.070 None 1.000 7 0 2002 2012
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4 		C-X-C motif chemokine receptor 4 0.362 0.923 1.8E-02
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		disease 0.070 None 0.857 6 0 2007 2015