Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 351
Gene Symbol: APP
APP
amyloid beta precursor protein 0.430 0.862 6.2E-02
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.900 0.967 1642 36 1987 2018
Entrez Id: 348
Gene Symbol: APOE
APOE
apolipoprotein E 0.352 0.931 1.7E-03
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.700 0.922 2328 9 1991 2018
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1
presenilin 1 0.490 0.690 0.98
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.700 0.939 488 40 1990 2018
Entrez Id: 6653
Gene Symbol: SORL1
SORL1
sortilin related receptor 1 0.619 0.483 1.1E-09
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.700 0.986 69 8 2004 2018
Entrez Id: 627
Gene Symbol: BDNF
BDNF
brain derived neurotrophic factor 0.382 0.828 0.70
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.600 0.976 124 7 1992 2018
Entrez Id: 1636
Gene Symbol: ACE
ACE
angiotensin I converting enzyme 0.367 0.897 1.6E-37
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.600 0.859 64 4 1998 2018
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.312 0.931 0.13
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.600 0.946 56 0 1989 2017
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
glycogen synthase kinase 3 beta 0.488 0.793 0.96
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.600 0.919 37 1 2000 2016
Entrez Id: 596
Gene Symbol: BCL2
BCL2
BCL2, apoptosis regulator 0.312 0.862 0.57
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.600 1.000 11 0 1996 2016
Entrez Id: 3643
Gene Symbol: INSR
INSR
insulin receptor 0.459 0.724 2.0E-05
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.590 1.000 9 0 2002 2016
Entrez Id: 3952
Gene Symbol: LEP
LEP
leptin 0.400 0.793 0.39
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.580 1.000 8 0 2005 2018
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
plasminogen activator, urokinase 0.434 0.690 2.1E-06
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.580 1.000 7 1 1994 2014
Entrez Id: 3481
Gene Symbol: IGF2
IGF2
insulin like growth factor 2 0.399 0.828 4.7E-02
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.550 1.000 5 0 2002 2015
Entrez Id: 4852
Gene Symbol: NPY
NPY
neuropeptide Y 0.469 0.690 0.16
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.550 0.600 5 0 2000 2016
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
insulin like growth factor 1 receptor 0.433 0.828 0.99
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.520 1.000 2 0 2005 2013
Entrez Id: 3630
Gene Symbol: INS
INS
insulin 0.458 0.828 0.32
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.520 1.000 1 0 1991 2007
Entrez Id: 581
Gene Symbol: BAX
BAX
BCL2 associated X, apoptosis regulator 0.450 0.862 0.30
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.510 1.000 1 0 1997 2011
Entrez Id: 5664
Gene Symbol: PSEN2
PSEN2
presenilin 2 0.567 0.517 2.4E-03
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.500 0.978 137 9 1995 2018
Entrez Id: 1191
Gene Symbol: CLU
CLU
clusterin 0.456 0.793 5.7E-05
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.500 0.963 82 4 1991 2018
Entrez Id: 54209
Gene Symbol: TREM2
TREM2
triggering receptor expressed on myeloid cells 2 0.572 0.552 4.0E-09
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.500 0.963 81 3 2007 2018
Entrez Id: 8301
Gene Symbol: PICALM
PICALM
phosphatidylinositol binding clathrin assembly protein 0.639 0.310 1.00
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.500 0.957 47 4 2009 2018
Entrez Id: 10347
Gene Symbol: ABCA7
ABCA7
ATP binding cassette subfamily A member 7 0.690 0.379 4.5E-55
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.500 1.000 34 8 2011 2018
Entrez Id: 23607
Gene Symbol: CD2AP
CD2AP
CD2 associated protein 0.642 0.448 0.29
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.500 1.000 11 1 2011 2018
Entrez Id: 1378
Gene Symbol: CR1
CR1
complement C3b/C4b receptor 1 (Knops blood group) 0.607 0.621 1.1E-33
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.460 1.000 6 3 2009 2018
Entrez Id: 7447
Gene Symbol: VSNL1
VSNL1
visinin like 1 0.652 0.345 0.49
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.450 1.000 5 1 2002 2016