DisGeNET - a database of gene-disease associations

Source: CLINGEN

Disease: Hypertrophic Cardiomyopathy ×

Gene: TRIM63 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	84676
Gene Symbol:	TRIM63

TRIM63

CUI:	C0007194
Disease:	Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy

0.640

Biomarker

CLINGEN

New cardiac and skeletal protein aggregate myopathy associated with combined MuRF1 and MuRF3 mutations.

25801283

2015

Entrez Id:	84676
Gene Symbol:	TRIM63

TRIM63

CUI:	C0007194
Disease:	Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy

0.640

Biomarker

CLINGEN

To determine the pathogenic role of TRIM63 in human hypertrophic cardiomyopathy (HCM).

22821932

2012

Entrez Id:	84676
Gene Symbol:	TRIM63

TRIM63

CUI:	C0007194
Disease:	Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy

0.640

Biomarker

CLINGEN

Muscle-specific RING finger 1 is a bona fide ubiquitin ligase that degrades cardiac troponin I.

15601779

2004

Entrez Id:	84676
Gene Symbol:	TRIM63

TRIM63

CUI:	C0007194
Disease:	Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy

0.640

Biomarker

CLINGEN

Identification of ubiquitin ligases required for skeletal muscle atrophy.

11679633

2001