Source: CLINGEN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 27030
Gene Symbol: MLH3
MLH3
CUI: C0009405
Disease: Hereditary Nonpolyposis Colorectal Neoplasms
Hereditary Nonpolyposis Colorectal Neoplasms 		0.500 Biomarker CLINGEN Biochemical characterization of MLH3 missense mutations does not reveal an apparent role of MLH3 in Lynch syndrome. 19156873

2009
Entrez Id: 27030
Gene Symbol: MLH3
MLH3
CUI: C0009405
Disease: Hereditary Nonpolyposis Colorectal Neoplasms
Hereditary Nonpolyposis Colorectal Neoplasms 		0.500 Biomarker CLINGEN Evidence that hMLH3 functions primarily in meiosis and in hMSH2-hMSH3 mismatch repair. 19483466

2009
Entrez Id: 27030
Gene Symbol: MLH3
MLH3
CUI: C0009405
Disease: Hereditary Nonpolyposis Colorectal Neoplasms
Hereditary Nonpolyposis Colorectal Neoplasms 		0.500 Biomarker CLINGEN The first functional study of MLH3 mutations found in cancer patients. 18521850

2008
Entrez Id: 27030
Gene Symbol: MLH3
MLH3
CUI: C0009405
Disease: Hereditary Nonpolyposis Colorectal Neoplasms
Hereditary Nonpolyposis Colorectal Neoplasms 		0.500 Biomarker CLINGEN Conditional nuclear localization of hMLH3 suggests a minor activity in mismatch repair and supports its role as a low-risk gene in HNPCC. 17203173

2007
Entrez Id: 27030
Gene Symbol: MLH3
MLH3
CUI: C0009405
Disease: Hereditary Nonpolyposis Colorectal Neoplasms
Hereditary Nonpolyposis Colorectal Neoplasms 		0.500 Biomarker CLINGEN Contributions by MutL homologues Mlh3 and Pms2 to DNA mismatch repair and tumor suppression in the mouse. 16204034

2005
Entrez Id: 27030
Gene Symbol: MLH3
MLH3
CUI: C0009405
Disease: Hereditary Nonpolyposis Colorectal Neoplasms
Hereditary Nonpolyposis Colorectal Neoplasms 		0.500 Biomarker CLINGEN Expression of the MutL homologue hMLH3 in human cells and its role in DNA mismatch repair. 16322221

2005