Source: CLINGEN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4437
Gene Symbol: MSH3
MSH3
CUI: C0009405
Disease: Hereditary Nonpolyposis Colorectal Neoplasms
Hereditary Nonpolyposis Colorectal Neoplasms 		0.300 Biomarker CLINGEN Exome Sequencing Identifies Biallelic MSH3 Germline Mutations as a Recessive Subtype of Colorectal Adenomatous Polyposis. 27476653

2016
Entrez Id: 4437
Gene Symbol: MSH3
MSH3
CUI: C0009405
Disease: Hereditary Nonpolyposis Colorectal Neoplasms
Hereditary Nonpolyposis Colorectal Neoplasms 		0.300 Biomarker CLINGEN Tissue-specific mismatch repair protein expression: MSH3 is higher than MSH6 in multiple mouse tissues. 23228367

2013
Entrez Id: 4437
Gene Symbol: MSH3
MSH3
CUI: C0009405
Disease: Hereditary Nonpolyposis Colorectal Neoplasms
Hereditary Nonpolyposis Colorectal Neoplasms 		0.300 Biomarker CLINGEN Association of low-risk MSH3 and MSH2 variant alleles with Lynch syndrome: probability of synergistic effects. 21128252

2011
Entrez Id: 4437
Gene Symbol: MSH3
MSH3
CUI: C0009405
Disease: Hereditary Nonpolyposis Colorectal Neoplasms
Hereditary Nonpolyposis Colorectal Neoplasms 		0.300 Biomarker CLINGEN The DNA mismatch repair genes Msh3 and Msh6 cooperate in intestinal tumor suppression. 10706084

2000
Entrez Id: 4437
Gene Symbol: MSH3
MSH3
CUI: C0009405
Disease: Hereditary Nonpolyposis Colorectal Neoplasms
Hereditary Nonpolyposis Colorectal Neoplasms 		0.300 Biomarker CLINGEN hMutSbeta, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA. 8805365

1996
Entrez Id: 4437
Gene Symbol: MSH3
MSH3
CUI: C0009405
Disease: Hereditary Nonpolyposis Colorectal Neoplasms
Hereditary Nonpolyposis Colorectal Neoplasms 		0.300 Biomarker CLINGEN hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6. 8942985

1996