Source: CLINGEN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6655
Gene Symbol: SOS2
SOS2
CUI: C0028326
Disease: Noonan Syndrome
Noonan Syndrome 		0.620 Biomarker CLINGEN We identified two novel genes, SOS2 and LZTR1, associated with Noonan syndrome, thereby expanding the molecular spectrum of RASopathies. 25795793

2015
Entrez Id: 6655
Gene Symbol: SOS2
SOS2
CUI: C0028326
Disease: Noonan Syndrome
Noonan Syndrome 		0.620 Biomarker CLINGEN Similar to NS-causing SOS1 mutations, the phenotype associated with SOS2 defects is characterized by normal development and growth, as well as marked ectodermal involvement. 26173643

2015
Entrez Id: 6655
Gene Symbol: SOS2
SOS2
CUI: C0028326
Disease: Noonan Syndrome
Noonan Syndrome 		0.620 Biomarker CLINGEN The RASopathies. 23875798

2013
Entrez Id: 6655
Gene Symbol: SOS2
SOS2
CUI: C0028326
Disease: Noonan Syndrome
Noonan Syndrome 		0.620 Biomarker CLINGEN Ras-guanine nucleotide exchange factor sos2 is dispensable for mouse growth and development. 10938118

2000