Source: CLINGEN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.310 Biomarker CLINGEN Hereditary Diffuse Gastric Cancer Syndrome: CDH1 Mutations and Beyond. 26182300

2015
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.310 Biomarker CLINGEN Germline CDH1 mutations in bilateral lobular carcinoma in situ. 24366306

2014
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.310 Biomarker CLINGEN Clinical evaluation of a multiple-gene sequencing panel for hereditary cancer risk assessment. 24733792

2014
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.310 Biomarker CLINGEN CDH1 germline mutations and the hereditary diffuse gastric and lobular breast cancer syndrome: a multicentre study. 23709761

2013
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.310 Biomarker CLINGEN The importance of E-cadherin binding partners to evaluate the pathogenicity of E-cadherin missense mutations associated to HDGC. 22850631

2013
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.310 Biomarker CLINGEN E-cadherin promotor methylation and mutation are inversely related to motility capacity of breast cancer cells. 23053649

2012
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.310 Biomarker CLINGEN Germline mutations of the E-cadherin gene in families with inherited invasive lobular breast carcinoma but no diffuse gastric cancer. 21271559

2011
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.310 Biomarker CLINGEN Germline E-cadherin mutations in familial lobular breast cancer. 17660459

2007
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.310 Biomarker CLINGEN Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis. 17097565

2006
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.310 Biomarker CLINGEN Inhibitory phosphorylation of the APC regulator Hct1 is controlled by the kinase Cdc28 and the phosphatase Cdc14. 10074450

1999
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.310 Biomarker CLINGEN Point mutation of the E-cadherin gene in invasive lobular carcinoma of the breast. 7961105

1994
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.310 Biomarker CLINGEN E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells. 2007622

1991