×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Malignant neoplasm of prostate
1.000
Biomarker
CTD_human
Several of the affected genes were known to be associated with aggressive prostate cancer such as loss of PTEN , CDH1, BCAR1 and gain of MYC.
29295717
2018
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Malignant neoplasm of prostate
1.000
Biomarker
CTD_human
The long tail of oncogenic drivers in prostate cancer.
29610475
2018
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Malignant neoplasm of prostate
1.000
Biomarker
CTD_human
Here we found that PML is frequently co-deleted with PTEN in metastatic human prostate cancer (CaP ).
29335545
2018
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Malignant neoplasm of prostate
1.000
Biomarker
CTD_human
A single-copy Sleeping Beauty transposon mutagenesis screen identifies new PTEN-cooperating tumor suppressor genes.
28319090
2017
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Malignant neoplasm of prostate
1.000
Biomarker
CTD_human
In this study, we investigated the role of SIRT1 in multiple human prostate cancer cell lines and prostate-specific PTEN knockout mouse model using resveratrol.
23248098
2013
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Malignant neoplasm of prostate
1.000
Biomarker
CTD_human
Dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced prostate carcinogenesis in CYP1A-humanized mice.
22581815
2012
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Malignant neoplasm of prostate
1.000
Biomarker
CTD_human
Common genetic alterations in prostate cancer include losses of NKX3.1 (8p21) and PTEN (10q23), gains of AR (the androgen receptor gene) and fusion of ETS family transcription factor genes with androgen-responsive promoters.
22610119
2012
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Malignant neoplasm of prostate
1.000
Biomarker
CTD_human
Since these miRNAs target PTEN (phosphatase and tensin homolog deleted on chromosome 10), we performed Western blot to confirm up-regulation of PTEN in PCa cells.
21714127
2011
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Malignant neoplasm of prostate
1.000
Biomarker
CTD_human
Regulation of phosphatase homologue of tensin protein expression by bone morphogenetic proteins in prostate epithelial cells.
21456062
2011
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Malignant neoplasm of prostate
1.000
Biomarker
CTD_human
Resveratrol regulates the PTEN/AKT pathway through androgen receptor-dependent and -independent mechanisms in prostate cancer cell lines.
20729295
2010
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Malignant neoplasm of prostate
1.000
Biomarker
CTD_human
Thus, ERG has a distinct role in prostate cancer progression and cooperates with PTEN haploinsufficiency to promote progression of HGPIN to invasive adenocarcinoma.
19396168
2009
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Malignant neoplasm of prostate
1.000
Biomarker
CTD_human
The pace of prostatic intraepithelial neoplasia development is determined by the timing of Pten tumor suppressor gene excision.
19081794
2008
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Malignant neoplasm of prostate
1.000
Biomarker
CTD_human
Integrative molecular concept modeling of prostate cancer progression.
17173048
2007
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Malignant neoplasm of prostate
1.000
Biomarker
CTD_human
PTEN and GSK3beta: key regulators of progression to androgen-independent prostate cancer.
16421604
2006
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
Malignant neoplasm of prostate
1.000
Biomarker
CTD_human
The identification of the second mutational event in 10 (43%) tumors establishes PTEN /MMAC1 as a main inactivation target of 10q loss in sporadic prostate cancer .
9371490
1997