DisGeNET - a database of gene-disease associations

Source: GENOMICS_ENGLAND

Disease: Cataract ×

Gene: TKFC ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	26007
Gene Symbol:	TKFC

TKFC

CUI:	C0086543
Disease:	Cataract

Cataract

0.300

Biomarker

GENOMICS_ENGLAND

We postulate that deficiency of TKFC causes disruption of endogenous fructose metabolism leading to generation of by-products that can cause cataract.

32004446

2020