Source: INFERRED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.800 CausalMutation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.800 CausalMutation CLINVAR The R882H DNMT3A mutation associated with AML dominantly inhibits wild-type DNMT3A by blocking its ability to form active tetramers. 24656771

2014
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.800 CausalMutation CLINVAR Molecular evaluation of DNMT3A and IDH1/2 gene mutation: frequency, distribution pattern and associations with additional molecular markers in normal karyotype Indian acute myeloid leukemia patients. 24606448

2014
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.800 CausalMutation CLINVAR Screening for mutation R882 in the DNMT3A gene in Chinese patients with hematological disease. 22744846

2012
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.800 CausalMutation CLINVAR The role of mutations in epigenetic regulators in myeloid malignancies. 22898539

2012
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.800 CausalMutation CLINVAR Cancer stem cells: Tracing clones. 22898540

2012
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.800 CausalMutation CLINVAR Retroviral oncogenes: a historical primer. 22898541

2012
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.800 CausalMutation CLINVAR [Analysis of DNMT3a gene mutations in acute myelogenous leukemia]. 21518476

2011
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.800 CausalMutation CLINVAR Impact of genetic features on treatment decisions in AML. 22160010

2011
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.800 CausalMutation CLINVAR DNMT3A mutations in acute myeloid leukemia. 21067377

2010
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.800 GeneticVariation CLINVAR

Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.800 Biomarker HPO