Source: INFERRED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.500 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014
Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.500 CausalMutation CLINVAR BRAF(L597) mutations in melanoma are associated with sensitivity to MEK inhibitors. 22798288

2012
Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.500 CausalMutation CLINVAR Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial. 22608338

2012
Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.500 CausalMutation CLINVAR Epidermal growth factor receptor blockers for the treatment of ovarian cancer. 21975775

2011
Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.500 CausalMutation CLINVAR Improved survival with vemurafenib in melanoma with BRAF V600E mutation. 21639808

2011
Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.500 CausalMutation CLINVAR Molecular pathogenesis and extraovarian origin of epithelial ovarian cancer--shifting the paradigm. 21683865

2011
Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.500 CausalMutation CLINVAR Inhibition of mutated, activated BRAF in metastatic melanoma. 20818844

2010
Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.500 CausalMutation CLINVAR Profound growth inhibition and apoptosis were observed in CI-1040-treated cancer cells with mutations in either KRAS or BRAF in comparison with the ovarian cancer cells containing wild-type sequences. 19018267

2008
Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.500 CausalMutation CLINVAR Mutations of the BRAF gene in human cancer. 12068308

2002