Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3077
Gene Symbol: HFE
HFE
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.700 GeneticVariation LHGDN Evaluation of HFE (hemochromatosis) mutations as genetic modifiers in sporadic AD and MCI. 15013567

2004

Entrez Id: 3077
Gene Symbol: HFE
HFE
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.700 GeneticVariation LHGDN We have examined the interaction between the C2 variant of the transferrin (TF) gene and the C282Y allele of the haemochromatosis (HFE) gene as risk factors for developing AD. 15060098

2004

Entrez Id: 3077
Gene Symbol: HFE
HFE
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.700 GeneticVariation LHGDN Although confirmation is required, these findings suggest that HFE mutations are associated with increased oxidative stress and Braak stage, and that HFE and APOE genotypes are different between AD patients, high pathology and low pathology controls. 12707938

2003