Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3566
Gene Symbol: IL4R
IL4R
CUI: C0004096
Disease: Asthma
Asthma 		0.400 GeneticVariation LHGDN The R551 IL4R variant was significantly associated with increased risk of asthma, most notably atopic asthma (combined OR, 1.6; P = .004). 17586032

2007
Entrez Id: 3566
Gene Symbol: IL4R
IL4R
CUI: C0004096
Disease: Asthma
Asthma 		0.400 GeneticVariation LHGDN The genetic association of IL4R with asthma might provide valuable insights into the pathogenesis of asthma. 17823973

2007
Entrez Id: 3566
Gene Symbol: IL4R
IL4R
CUI: C0004096
Disease: Asthma
Asthma 		0.400 Biomarker LHGDN IL4R alpha mutations are associated with asthma exacerbations and mast cell/IgE expression. 17170387

2007
Entrez Id: 3566
Gene Symbol: IL4R
IL4R
CUI: C0004096
Disease: Asthma
Asthma 		0.400 GeneticVariation LHGDN Polymorphisms in the interleukin-4 receptor alpha chain: association with traits of allergy and asthma in an admixed population in Hawaii. 14984008

2003
Entrez Id: 3566
Gene Symbol: IL4R
IL4R
CUI: C0004096
Disease: Asthma
Asthma 		0.400 GeneticVariation LHGDN These data suggest that the IL-4R alpha chain 576R/R genotypes confer genetic susceptibility to allergic asthma in Chinese. 12940513

2003
Entrez Id: 3566
Gene Symbol: IL4R
IL4R
CUI: C0004096
Disease: Asthma
Asthma 		0.400 Biomarker LHGDN These data suggest that variations in IL4RA contribute to elevated total serum IgE levels, and interaction between IL4RA and IL13 markedly increases an individual's susceptibility to asthma. 11709756

2002
Entrez Id: 3566
Gene Symbol: IL4R
IL4R
CUI: C0004096
Disease: Asthma
Asthma 		0.400 GeneticVariation LHGDN Asthma and IL-4 receptor alpha gene variants. 12047364

2002