Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.400 AlteredExpression LHGDN Elevated plasma PAI-1 activity was independently associated with coronary microvascular dysfunction, which suggests that plasma PAI-1 activity is an important clue linking hypofibrinolysis to the development of atherosclerosis. 17322633

2007

Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.400 Biomarker LHGDN Studies with transgenic mice have revealed a functional role for PAI-1 in wound healing, atherosclerosis, metabolic disturbances such as obesity and insulin resistance, tumor angiogenesis, chronic stress, bone remodeling, asthma, rheumatoid arthritis, fibrosis, glomerulonephritis and sepsis. 15634264

2005