Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.400 Biomarker LHGDN Inhibition of cyclin D1 expression by cyclin D1 shRNAs in human oral squamous cell carcinoma cells is associated with increased cisplatin chemosensitivity. 18942709

2009
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.400 AlteredExpression LHGDN Susceptible genes and molecular pathways related to heavy ion irradiation in oral squamous cell carcinoma cells. 18514338

2008
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.400 AlteredExpression LHGDN Overexpression of CyclinD1 and underexpression of p16 correlate with lymph node metastases in laryngeal squamous cell carcinoma in Chinese patients. 18787961

2008
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.400 GeneticVariation LHGDN Thus our findings suggest that CCND1 (G870A) polymorphism may be associated with increased risk of SCC of the uterine cervix in north Indian women. 18548202

2008
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.400 GeneticVariation LHGDN P21/ WAF1 and cyclin D1 variants and oral squamous cell carcinoma. 18251939

2008
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.400 AlteredExpression LHGDN Abrogation of the p16-retinoblastoma-cyclin D1 pathway in head and neck squamous cell carcinomas. 17549378

2007
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.400 AlteredExpression LHGDN The multi-step process of human skin carcinogenesis: a role for p53, cyclin D1, hTERT, p16, and TSP-1. 17198740

2007
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.400 AlteredExpression LHGDN Cyclin D1-positive nuclear staining was overexpressed in 13/21 SCC (61.9%) and in one case of erythoplasia of Queyrat. 17695500

2007
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.400 AlteredExpression LHGDN We observed the expression patterns and frequencies of p53, p16, and cyclin D1 in esophageal dysplasia and in esophageal squamous cell carcinomas. 17060721

2006
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.400 AlteredExpression LHGDN Prolyl isomerase Pin1 expression predicts prognosis in patients with esophageal squamous cell carcinoma and correlates with cyclinD1 expression. 16820873

2006
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.400 AlteredExpression LHGDN Activation of STAT 5-cyclin D1 pathway in chewing tobacco mediated oral squamous cell carcinoma. 16172916

2005
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.400 GeneticVariation LHGDN Cyclin D1 genotype in areca-associated oral squamous cell carcinoma. 12694349

2003
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.400 AlteredExpression LHGDN In 51 primary tumor samples from patients with squamous cell carcinoma of the p.o. tongue, there was a significant correlation between increased levels of the activated form of Stat3, phosphorylated-Stat3, and increased levels of cyclin D1 (P < 0.0001). 12067972

2002
Entrez Id: 595
Gene Symbol: CCND1
CCND1
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.400 AlteredExpression LHGDN This study investigates the expression of p53, epidermal growth factor receptor (EGFR), transforming growth factor-alpha (TGF-alpha), and cyclin D1 in VC, verrucous hyperplasia (VH), and classic SCC of the head and neck. 12607604

2002