Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 PosttranslationalModification LHGDN DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications. 18538736

2008

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 AlteredExpression LHGDN Positive KL-6 mucin expression combined with decreased membranous beta-catenin expression indicates worse prognosis in colorectal carcinoma. 18949395

2008

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 AlteredExpression LHGDN Nuclear beta-catenin expression as a prognostic factor in advanced colorectal carcinoma. 18609711

2008

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 Biomarker LHGDN Mutated in colorectal cancer, a putative tumor suppressor for serrated colorectal cancer, selectively represses beta-catenin-dependent transcription. 18591935

2008

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 Biomarker LHGDN Beta-catenin expression in relation to genetic instability and prognosis in colorectal cancer. 17203186

2007

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 AlteredExpression LHGDN Cell-cycle and apoptosis regulators (p16INK4A, p21CIP1, beta-catenin, survivin, and hTERT) and morphometry-defined MPECs predict metachronous cancer development in colorectal adenoma patients. 17641414

2007

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 Biomarker LHGDN A positive feedback loop between hepatocyte growth factor receptor and beta-catenin sustains colorectal cancer cell invasive growth. 16953230

2007

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 Biomarker LHGDN Prognostic significance of beta-catenin in colorectal cancer with liver metastasis. 17168211

2006

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 Biomarker LHGDN Novel cross talk of Kruppel-like factor 4 and beta-catenin regulates normal intestinal homeostasis and tumor repression. 16507986

2006

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 AlteredExpression LHGDN Regulation of AKT1 expression by beta-catenin/Tcf/Lef signaling in colorectal cancer cells. 15888491

2005

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 AlteredExpression LHGDN Mutations in APC, CTNNB1 and K-ras genes and expression of hMLH1 in sporadic colorectal carcinomas from the Netherlands Cohort Study. 16356174

2005

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 AlteredExpression LHGDN Pin1 overexpression in colorectal cancer and its correlation with aberrant beta-catenin expression. 16124054

2005

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 Biomarker LHGDN MUC1 and nuclear beta-catenin are coexpressed at the invasion front of colorectal carcinomas and are both correlated with tumor prognosis. 15102686

2004

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 AlteredExpression LHGDN Relation of E-cadherin and beta-catenin expression to pit pattern in colorectal cancer. 15289833

2004

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 Biomarker LHGDN Prognostic and diagnostic significance of beta-catenin nuclear immunostaining in colorectal cancer. 14977843

2004

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 Biomarker LHGDN Nuclear beta-catenin accumulation as a prognostic factor in Dukes' D human colorectal cancers. 15254684

2004

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 AlteredExpression LHGDN Activator protein 2alpha associates with adenomatous polyposis coli/beta-catenin and Inhibits beta-catenin/T-cell factor transcriptional activity in colorectal cancer cells. 15331612

2004

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 AlteredExpression LHGDN Expression level of Wnt signaling components possibly influences the biological behavior of colorectal cancer in different age groups. 15126105

2004

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 GeneticVariation LHGDN The APC/beta-catenin pathway in ulcerative colitis-related colorectal carcinomas: a mutational analysis. 11920497

2002

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 AlteredExpression LHGDN Nuclear beta-catenin expression is closely related to ulcerative growth of colorectal carcinoma. 11953860

2002

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 AlteredExpression LHGDN Elevated protein expression of cyclin D1 and Fra-1 but decreased expression of c-Myc in human colorectal adenocarcinomas overexpressing beta-catenin. 12209953

2002