Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 Biomarker LHGDN Trichostatin A causes p53 to switch oxidative-damaged colorectal cancer cells from cell cycle arrest into apoptosis. 18419600

2008

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 GeneticVariation LHGDN Colorectal carcinomas from Middle East. Molecular and tissue microarray analysis of genomic instability pathways. 18176677

2008

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 AlteredExpression LHGDN Abberant crypt foci -- importance in colorectal carcinogenesis and expression of p53 and mdm2: a changing concept. 18080767

2008

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 AlteredExpression LHGDN Detection of colorectal cancer cells from feces using quantitative real-time RT-PCR for colorectal cancer diagnosis. 19016757

2008

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 GeneticVariation LHGDN We have analyzed the prevalence of MDM2 gene amplifications and SNP309 in 284 colorectal tumors using a relatively new highly sensitive PCR/ligase detection reaction method in relation to TP53 mutational status and genomic instability. 18314481

2008

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 AlteredExpression LHGDN Inhibition of cell-cycle progression in human colorectal carcinoma Lovo cells by andrographolide. 18619950

2008

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 Biomarker LHGDN Proline oxidase, a p53-induced gene, targets COX-2/PGE2 signaling to induce apoptosis and inhibit tumor growth in colorectal cancers. 18794809

2008

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 GeneticVariation LHGDN GSTM, GSTT and p53 polymorphisms as modifiers of clinical outcome in colorectal cancer. 18630481

2008

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 GeneticVariation LHGDN Association of p53 codon 72 polymorphism with liver metastases of colorectal cancers positive for p53 overexpression. 18988302

2008

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 GeneticVariation LHGDN Genetic alterations of APC, K-ras, p53, MSI, and MAGE in Korean colorectal cancer patients. 17704924

2008

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 GeneticVariation LHGDN Expression of p53 in colorectal carcinoma: correlation with clinicopathologic features. 17198452

2007

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 GeneticVariation LHGDN The differentially mutational spectra of the APC, K-ras, and p53 genes in sporadic colorectal cancers from Taiwanese patients. 18265644

2007

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 GeneticVariation LHGDN Mutations in TP53 are a prognostic factor in colorectal hepatic metastases undergoing surgical resection. 17259658

2007

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 AlteredExpression LHGDN Association of angiogenesis markers with lymph node metastasis in early colorectal cancer. 17709727

2007

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 GeneticVariation LHGDN Tumour selection advantage of non-dominant negative P53 mutations in homozygotic MDM2-SNP309 colorectal cancer cells. 16825434

2007

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 AlteredExpression LHGDN Serum p53 antibodies as an early detection marker in colorectal cancer. 18019675

2007

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 GeneticVariation LHGDN Involvement of Kruppel-like factor 6 (KLF6) mutation in the development of nonpolypoid colorectal carcinoma. 17663506

2007

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 GeneticVariation LHGDN New mutations in the human p53 gene--a regulator of the cell cycle and carcinogenesis. 17447881

2007

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 Biomarker LHGDN Combined analysis of COX-2 and p53 expressions reveals synergistic inverse correlations with microsatellite instability and CpG island methylator phenotype in colorectal cancer. 16820091

2006

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 GeneticVariation LHGDN Molecular detection of TP53, Ki-Ras and p16INK4A promoter methylation in plasma of patients with colorectal cancer and its association with prognosis. Results of a 3-year GOIM (Gruppo Oncologico dell'Italia Meridionale) prospective study. 16760301

2006

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 GeneticVariation LHGDN Analysis of P53 mutations and their expression in 56 colorectal cancer cell lines. 16418264

2006

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 GeneticVariation LHGDN Specific TP53 and/or Ki-ras mutations as independent predictors of clinical outcome in sporadic colorectal adenocarcinomas: results of a 5-year Gruppo Oncologico dell'Italia Meridionale (GOIM) prospective study. 15923430

2005

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 AlteredExpression LHGDN Correlation between hMLH1/hMSH2 and p53 protein expression in sporadic colorectal cancer. 15816455

2005

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 AlteredExpression LHGDN Prognostic significance of bcl-2 and p53 expression in colorectal carcinoma. 16358373

2005

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 AlteredExpression LHGDN p53, Bcl-2 and C-Myc expressions in colorectal carcinoma associated with schistosomiasis in Egypt. 16308474

2005