Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 GeneticVariation LHGDN Angiotensin II type 1 receptor gene polymorphism predicts development of hypertension and metabolic syndrome. 19023273

2009
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 GeneticVariation LHGDN Interacting effect of genetic variants of angiotensin II type 1 receptor on susceptibility to essential hypertension in Northern Han Chinese. 18633425

2009
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 GeneticVariation LHGDN In conclusion, there is insufficient evidence that polymorphisms in the AGTR1 gene are risk factors for hypertension. 18641512

2008
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 Biomarker LHGDN Autoantibody against AT1 receptor from preeclamptic patients induces vasoconstriction through angiotensin receptor activation. 18622242

2008
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 GeneticVariation LHGDN In addition, angiotensin-converting enzyme and AT1R A1166C polymorphisms were associated or marginally associated with incident hypertension among postmenopausal women and those with inadequate calcium and vitamin D intakes. 18550936

2008
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 GeneticVariation LHGDN Investigation of major genetic polymorphisms in the Renin-Angiotensin-aldosterone system in subjects with young-onset hypertension selected by a targeted-screening system at university. 17190732

2007
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 AlteredExpression LHGDN Gene polymorphism of angiotensin-converting enzyme and angiotensin II type 1 receptor in patients with congestive heart failure. 18767410

2007
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 GeneticVariation LHGDN Associations of the angiotensin II type 1 receptor A1166C and the endothelial NO synthase G894T gene polymorphisms with silent subcortical white matter lesions in essential hypertension. 16109907

2005
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 Biomarker LHGDN Because angiotensin II responsiveness of AT1 receptors can be specifically modified by AT1/B2 receptor dimerization, we determined the AT1 receptor dimerization status in an experimental model of hypertension. 16012192

2005
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 GeneticVariation LHGDN Gene polymorphisms of the renin-angiotensin-aldosterone system and the risk of ischemic stroke: a role of the A1166C/AT1 gene variant. 15480097

2004
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 GeneticVariation LHGDN A1166C variant of angiotensin II type 1 receptor gene is associated with severe hypertension in pregnancy independently of T235 variant of angiotensinogen gene. 15042429

2004
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 GeneticVariation LHGDN These data suggest that the (-535)T allele of AGTR1 and (-344)T allele of CYP11B2 may increase hypertension risk among African Americans but not among Latinos. 15545843

2004
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 GeneticVariation LHGDN Genetic variants of angiotensin II receptors and cardiovascular risk in hypertension. 12925562

2003
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 GeneticVariation LHGDN Angiotensin II type 1 receptor gene polymorphism and essential hypertension in Serbian population. 12482634

2003
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 Biomarker LHGDN AT1R gene contributed to T2DM complicated by hypertension, but is only associated with cases of elevated systolic blood pressure. 12390711

2002
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 GeneticVariation LHGDN Gene polymorphisms of the renin-angiotensin-aldosterone system and essential arterial hypertension in childhood. 12597535

2002
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 Biomarker LHGDN Stimulation of cardiac apoptosis in essential hypertension: potential role of angiotensin II. 11799082

2002
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 GeneticVariation LHGDN A1166C polymorphism of the angiotensin II type 1 receptor gene and essential hypertension in Han, Tibetan and Yi populations. 12358135

2002
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 Biomarker LHGDN [Influence of angiotensin II type 1 receptor gene polymorphism on patients with essential hypertension complicated by brain infarction]. 12048678

2002