Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.700 GeneticVariation LHGDN Endothelial nitric oxide synthase genetic variation and essential hypertension risk in Han Chinese: the Fangshan study. 18769442

2009

Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.700 GeneticVariation LHGDN Endothelial nitric oxide synthase gene haplotypes and circulating nitric oxide levels significantly associate with risk of essential hypertension. 18325347

2008

Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.700 GeneticVariation LHGDN The 894T and -786C alleles of the NOS3 gene were significantly associated with both hypertension and CVD in renal allograft recipients. 18331440

2008

Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.700 GeneticVariation LHGDN In summary, the NOS3 IVS25+15 is directly associated with blood pressure and hypertension in white Europeans. 18246059

2008

Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.700 GeneticVariation LHGDN Association of eNOS Glu298Asp gene polymorphism with essential hypertension in Asian Indians. 17935708

2008

Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.700 GeneticVariation LHGDN Lack of association between endothelial nitric oxide synthase gene polymorphisms, microalbuminuria and endothelial dysfunction in hypertensive men. 17563560

2007

Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.700 GeneticVariation LHGDN NOS3 T-786C was also related to hypertension (p=0.049). 17126309

2007

Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.700 GeneticVariation LHGDN It was found that the frequencies of b/b, b/a and a/a genotypes of the eNOS4 gene were 84.06%, 15.22% and 0.72% in the control group, and 81.46%, 15.89% and 2.65% in the hypertension group, respectively. 17492127

2007

Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.700 GeneticVariation LHGDN Association of endothelial nitric oxide synthase gene G894T polymorphism with essential hypertension in an adult Pakistani Pathan population. 16765468

2007

Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.700 GeneticVariation LHGDN While endothelial nitric oxide synthase (eNOS) haplotypes have been associated with HT, it is unknown whether eNOS genotypes/haplotypes are associated with altered susceptibility to HT in patients with T2DM. 16427644

2006

Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.700 Biomarker LHGDN our results suggest that eNOS gene may have gender-specific and age-dependent effects on DBP and the development of hypertension risk. 16041245

2005

Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.700 GeneticVariation LHGDN Associations of the angiotensin II type 1 receptor A1166C and the endothelial NO synthase G894T gene polymorphisms with silent subcortical white matter lesions in essential hypertension. 16109907

2005

Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.700 GeneticVariation LHGDN [NOS3 gene polymorphism and left ventricular hypertrophy in patients with essential hypertension]. 12494183

2002

Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.700 GeneticVariation LHGDN The endothelial nitric oxide synthase Glu298Asp polymorphism has been suggested to play a role in the development of hypertension, atherosclerosis and coronary artery disease. 12359981

2002