DisGeNET - a database of gene-disease associations

Source: LHGDN

Disease: Chronic Lymphocytic Leukemia ×

Gene: TCL1A ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	8115
Gene Symbol:	TCL1A

TCL1A

CUI:	C0023434
Disease:	Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

0.100

AlteredExpression

LHGDN

The results indicate that Tcl1 overexpression causes B-CLL by directly enhancing NF-kappaB activity and inhibiting AP-1.

19064921

2008

Entrez Id:	8115
Gene Symbol:	TCL1A

TCL1A

CUI:	C0023434
Disease:	Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

0.100

AlteredExpression

LHGDN

Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181.

17178851

2006

Entrez Id:	8115
Gene Symbol:	TCL1A

TCL1A

CUI:	C0023434
Disease:	Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

0.100

Biomarker

LHGDN

Tcl1 as a model for lymphomagenesis.

15325703

2004