Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.500 AlteredExpression LHGDN CCL5 increases lung cancer migration via PI3K, Akt and NF-kappaB pathways. 19073147

2009
Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.500 PosttranslationalModification LHGDN The potential role of Akt phosphorylation in human cancers. 18409144

2008
Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.500 AlteredExpression LHGDN Targeting of AKT1 enhances radiation toxicity of human tumor cells by inhibiting DNA-PKcs-dependent DNA double-strand break repair. 18644989

2008
Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.500 GeneticVariation LHGDN Activating E17K mutation in the gene encoding the protein kinase AKT1 in a subset of squamous cell carcinoma of the lung. 18256540

2008
Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.500 Biomarker LHGDN AKT1 amplification regulates cisplatin resistance in human lung cancer cells through the mammalian target of rapamycin/p70S6K1 pathway. 17616691

2007
Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.500 Biomarker LHGDN Effects of GM-CSF and M-CSF on tumor progression of lung cancer: roles of MEK1/ERK and AKT/PKB pathways. 16820947

2006
Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.500 AlteredExpression LHGDN Epidermal growth factor and hypoxia-induced expression of CXC chemokine receptor 4 on non-small cell lung cancer cells is regulated by the phosphatidylinositol 3-kinase/PTEN/AKT/mammalian target of rapamycin signaling pathway and activation of hypoxia inducible factor-1alpha. 15802268

2005