Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 Biomarker LHGDN Together, our data show that a beta-catenin-RET kinase pathway is a critical contributor to the development and metastasis of human thyroid carcinoma. 18316596

2008

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 PosttranslationalModification LHGDN Immunohistochemical analyses for RASSF1A and beta-catenin were performed in 28 matched primary and metastatic tumors. 17526942

2006

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 AlteredExpression LHGDN Reduced membranous expression of beta-catenin was detected in the cases with metastasis (11/14). 16865250

2006

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 Biomarker LHGDN Conversely, significantly reduced rates of lymph-node metastases were observed in alpha- and beta-catenin-positive T1 and T2 SCCs. 15916880

2005

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 Biomarker LHGDN Both abnormal expression of E-cadherin and alpha-catenin significantly correlated with differentiation, lymph node and liver metastases (P<0.05, respectively), whereas aberrant beta-catenin expression only correlated with lymph node and liver metastases (P<0.001). 12532469

2003

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 AlteredExpression LHGDN And the aberrant expression of beta-catenin protein was statistically correlated to the lymph node metastasis in esophageal cancer. 12478897

2002