Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm 		0.900 AlteredExpression LHGDN Surprisingly, little is known about the role and regulation of hdm2 in pancreatic tumors, a large proportion (50-75%) of which contain mutant p53. 19029954

2009
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm 		0.900 GeneticVariation LHGDN Suppression of inhibitor of differentiation 2, a target of mutant p53, is required for gain-of-function mutations. 18701504

2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm 		0.900 GeneticVariation LHGDN Evaluation of clinical relevance of examining K-ras, p16 and p53 mutations along with allelic losses at 9p and 18q in EUS-guided fine needle aspiration samples of patients with chronic pancreatitis and pancreatic cancer. 17659731

2007
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm 		0.900 GeneticVariation LHGDN Pancreatic tumor cell lines, CRL1420, which contains elevated levels of mutant p53, and CRL1682, with no detectable p53 protein, were stably transfected with the exogenous wild-type p53 gene. 17651038

2007
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm 		0.900 AlteredExpression LHGDN Expression of Gadd45a and p53 proteins in human pancreatic cancer: potential effects on clinical outcomes. 17230496

2007
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm 		0.900 GeneticVariation LHGDN Detecting low-abundance p16 and p53 mutations in pancreatic juice using a novel assay: heteroduplex analysis of limiting dilution PCRs. 17106238

2006
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm 		0.900 GeneticVariation LHGDN Immortalizing the complexity of cancer metastasis: genetic features of lethal metastatic pancreatic cancer obtained from rapid autopsy. 15846069

2005