Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 AlteredExpression LHGDN Ubiquitination by TOPORS regulates the prostate tumor suppressor NKX3.1. 18077445

2008

Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 AlteredExpression LHGDN Loss of NKX3.1 favors vascular endothelial growth factor-C expression in prostate cancer. 18974119

2008

Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 AlteredExpression LHGDN Expression of Nkx3.1 enhances 17beta-estradiol anti-tumor action in PC3 human prostate cancer cells. 17486276

2007

Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 AlteredExpression LHGDN NKX3.1 stabilizes p53, inhibits AKT activation, and blocks prostate cancer initiation caused by PTEN loss. 16697957

2006

Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 AlteredExpression LHGDN p53 overexpression represses androgen-mediated induction of NKX3.1 in a prostate cancer cell line. 17202838

2006

Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 GeneticVariation LHGDN Germ-line mutation of NKX3.1 cosegregates with hereditary prostate cancer and alters the homeodomain structure and function. 16397218

2006

Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker LHGDN Identification of an inhibitory cis-element in the promoter region of human homeobox gene NKX3.1. 16845664

2006

Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 AlteredExpression LHGDN Deletion, methylation, and expression of the NKX3.1 suppressor gene in primary human prostate cancer. 15734999

2005

Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker LHGDN Analysis of androgen regulated homeobox gene NKX3.1 during prostate carcinogenesis. 15311057

2004