Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 864
Gene Symbol: RUNX3
RUNX3
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.400 AlteredExpression LHGDN Enhancer of zeste homologue 2 (EZH2) down-regulates RUNX3 by increasing histone H3 methylation. 18430739

2008

Entrez Id: 864
Gene Symbol: RUNX3
RUNX3
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.400 PosttranslationalModification LHGDN Helicobacter pylori infection is an independent risk factor for Runx3 methylation in gastric cancer. 18097595

2008

Entrez Id: 864
Gene Symbol: RUNX3
RUNX3
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.400 PosttranslationalModification LHGDN Aberrant methylation within RUNX3 CpG island associated with the nuclear and mitochondrial microsatellite instability in sporadic gastric cancers. Results of a GOIM (Gruppo Oncologico dell'Italia Meridionale) prospective study. 17591800

2007

Entrez Id: 864
Gene Symbol: RUNX3
RUNX3
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.400 PosttranslationalModification LHGDN Spreading of methylation within RUNX3 CpG island in gastric cancer. 16367921

2006

Entrez Id: 864
Gene Symbol: RUNX3
RUNX3
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.400 Biomarker LHGDN How does the human RUNX3 gene induce apoptosis in gastric cancer? Latest data, reflections and reactions. 16627973

2006

Entrez Id: 864
Gene Symbol: RUNX3
RUNX3
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.400 AlteredExpression LHGDN Frequent downregulation of the runt domain transcription factors RUNX1, RUNX3 and their cofactor CBFB in gastric cancer. 15386419

2005

Entrez Id: 864
Gene Symbol: RUNX3
RUNX3
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.400 Biomarker LHGDN RUNX3, a novel tumor suppressor, is frequently inactivated in gastric cancer by protein mislocalization. 16140942

2005

Entrez Id: 864
Gene Symbol: RUNX3
RUNX3
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.400 PosttranslationalModification LHGDN Promoter methylation status of DAP-kinase and RUNX3 genes in neoplastic and non-neoplastic gastric epithelia. 12824905

2003