Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.700 Biomarker LHGDN Gain and/or amplification of PIK3CA gene, encoding the catalytic subunit of phosphatidylinositol 3-kinase (p110 alpha) and its increased expression are associated with enhanced PI3K activity in ovarian cancer cell lines. 17377809

2007
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.700 AlteredExpression LHGDN Taken together, our data demonstrate that IGF-I induces COX-2 expression in human ovarian cancer cells, which is mediated by three parallel signaling cascades--PI3K, MAPK, and PKC pathways that differentially regulate COX-2 expression at transcriptional and post-transcriptional levels. 17341442

2007
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.700 GeneticVariation LHGDN PIK3CA mutations in ovarian cancer. 16203798

2005